Publications by authors named "Carolyn Fong"
Expression of prostaglandin D synthase and the prostaglandin D2 receptors DP and CRTH2 in human nasal mucosa.
Prostaglandins Other Lipid Mediat
January 2004
Article Synopsis
- Prostaglandin D2 (PGD2) is released from mast cells during allergic reactions and is linked to nasal congestion.
- Researchers examined the distribution of hematopoietic prostaglandin D synthase (PGDS) and the PGD2 receptors (DP and CRTH2) in nasal mucosa from healthy individuals and those with chronic rhinosinusitis polyposis.
- The findings showed that in healthy mucosa, PGDS was limited to a few mast cells, while in polyposis, PGDS was found in various inflammatory cells, and both PGD2 receptors were present in eosinophils and some T cells, suggesting their involvement in upper airway inflammation.