Publications by authors named "Carolyn Fang"

This study evaluated the association between age at first full-term pregnancy (FFTP) and mammographic breast density (MBD) in postmenopausal women. 1,034 women, age 50-69y, were recruited from the Flemish (Belgium) population-based breast cancer screening program. Participants completed a questionnaire on lifestyle and reproductive factors.

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  • The study explores how body compassion—viewing one's body with kindness and mindfulness—may help colorectal cancer (CRC) patients adjust psychosocially to their condition and improve their quality of life (QOL).
  • Fifty-four CRC patients completed surveys measuring body compassion, distress, loneliness, resilience, and QOL, validating a new measure called the Body Compassion Scale (BCS) with strong reliability (α = 0.94).
  • Results indicated that patients with metastatic cancer and those currently in treatment reported lower body compassion, while higher body compassion correlated with reduced distress and loneliness, and increased resilience and QOL, especially linked to specific BCS subscales like defusion.
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  • Cervical cancer screening rates are notably low among Korean American women in the US, prompting the development of an educational intervention aimed at improving their knowledge and beliefs about screening.
  • The intervention, which included cultural cancer education and navigation services, significantly enhanced knowledge and reduced perceived barriers to screening compared to a control group.
  • Ultimately, while the program improved knowledge and beliefs, it was the navigation services that most effectively increased actual screening rates, indicating their importance in health intervention strategies for underserved populations.
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African American (AA) individuals experience food insecurity at twice the rate of the general population. However, few patients are screened for these measures in the oncology setting. The primary aim of this study was to evaluate associations between food insecurity and dietary quality in AA patients with gastrointestinal (GI) malignancies.

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Background: The majority of Chinese Americans is foreign-born, and it is well-documented that immigration to the United States (US) leads to increased risk for chronic diseases including type 2 diabetes. Increased disease risk has been attributed to changes in lifestyle behaviors following immigration, but few studies have considered the psychosocial impact of immigration upon biomarkers of disease risk.

Purpose: To examine associations of psychological stress and social isolation with markers of type 2 diabetes risk over time among US Chinese immigrants.

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Background: Latinas experience the greatest cervical cancer incidence compared with other ethnic/racial groups in the United States (US) due in part to significant disparities in screening uptake. Social and structural conditions that impede access to and participation in screening include language barriers, concerns about documentation status, logistical issues (e.g.

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Numbers of aggressive prostate cancer (aPC) cases are rising, but only a few risk factors have been identified. In this study, we introduce a systematic approach to integrate geospatial data into external exposome research using aPC cases from Pennsylvania. We demonstrate the association between several area-level exposome measures across five Social Determinants of Health domains (SDOH) and geographic areas identified as having elevated odds of aPC.

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The COVID-19 pandemic's effect on established Chinese ethnic enclaves, which faced socio-economic disruptions as well as anti-Asian sentiment, is unknown. We compared the pandemic's effect on social capital among residents and non-residents of Chinese ethnic enclaves in Philadelphia. Despite declines in group participation and citizenship activity (joining with others or speaking with local officials to address a neighborhood problem), the pandemic increased support received from other individuals and cognitive social capital (e.

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Purpose: Delays initiating cancer therapy are increasingly common, impact outcomes, and have implications for health equity. However, it remains unclear (1) whether patients' beliefs regarding acceptable diagnostic to treatment intervals align with current guidelines, and (2) to what degree psychological factors contribute to longer intervals. We conducted a qualitative study with patients and cancer care team members ("providers").

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Background: The engagement of family caregivers in oncology is not universal or systematic.

Objective: We implemented a process intervention (ie, patient-caregiver portal system) with an existing patient portal system to (1) allow a patient to specify their caregiver and communication preferences with that caregiver, (2) connect the caregiver to a unique caregiver-specific portal page to indicate their needs, and (3) provide an electronic notification of the dyad's responses to the care team to inform clinicians and connect the caregiver to resources as needed.

Methods: We assessed usability and satisfaction with this patient-caregiver portal system among patients with cancer receiving palliative care, their caregivers, and clinicians.

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African American, American Indian and Alaska Native, Hispanic (or Latinx), Native Hawaiian, and other Pacific Islander groups are underrepresented in the biomedical workforce, which is one of the barriers to addressing cancer disparities among minority populations. The creation of a more inclusive biomedical workforce dedicated to reducing the burden of cancer health disparities requires structured, mentored research and cancer-related research exposure during the earlier stages of training. The Summer Cancer Research Institute (SCRI) is a multicomponent 8-week intensive summer program funded under the Partnership between a Minority Serving Institute and a National Institutes of Health-designated Comprehensive Cancer Center.

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Objective: This study examined the cross-sectional relationships between neighborhood social composition and gentrification, and acculturation stressors.

Methods: Person-level data came from first-generation Chinese immigrants enrolled in the Immigrant Enclaves Study (Philadelphia, Pennsylvania, baseline 2018-2020, N = 512). A validated scale was used to assess 22 stressors associated with migration or acculturation.

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  • The study looks at how different ways to define aggressive prostate cancer (PCan) can help find communities where men might need help with this cancer.
  • Researchers used data from Pennsylvania to see how different definitions change the number and locations of cases identified.
  • They found that one specific definition (D2) was the best for matching areas with higher death rates from prostate cancer and might help scientists do better studies in the future.
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  • Delays in cancer treatment significantly impact vulnerable populations, affecting their overall experience and outcomes.
  • A machine learning model was developed to predict the likelihood of treatment delays over 60 days using electronic health records and neighborhood data.
  • The analysis included 6,409 patients diagnosed with various cancers, evaluating different machine learning methods for their ability to identify at-risk individuals based on clinical and demographic data.
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  • * Participants completed a survey using established questionnaires, revealing a generally high QOL with a median global health score of 75.0, although some symptoms were noted.
  • * The research found that younger patients and those using opiates reported lower QOL and experienced more severe symptoms like reflux and odynophagia.
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African American, American Indian and Alaska Native, Hispanic (or Latinx), Native Hawaiian, and other Pacific Islander groups are underrepresented in the biomedical workforce, which is one of the barriers to addressing cancer disparities among minority populations. The creation of a more inclusive biomedical workforce dedicated to reducing the burden of cancer health disparities requires structured, mentored research and cancer-related research exposure during the earlier stages of training. The Summer Cancer Research Institute (SCRI), a multicomponent 8-week intensive summer program funded under the Partnership between a Minority Serving Institute and a National Institutes of Health-designated Comprehensive Cancer Center.

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Identification of procedures using International Classification of Diseases or Healthcare Common Procedure Coding System codes is challenging when conducting medical claims research. We demonstrate how Pointwise Mutual Information can be used to find associated codes. We apply the method to an investigation of racial differences in breast cancer outcomes.

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Background: Additional evaluations, including second opinions, before breast cancer surgery may improve care, but may cause detrimental treatment delays that could allow disease progression.

Aims: We investigate the timing of surgical delays that are associated with survival benefits conferred by preoperative encounters versus the timing that are associated with potential harm.

Methods And Results: We investigated survival outcomes of SEER Medicare patients with stage 1-3 breast cancer using propensity score-based weighting.

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Background: Caregivers are rarely assessed for caregiving-related strain. This study explored the psychometric properties of the caregiving-related physical, emotional, and financial strain questions in the National Alliance for Caregiving's (NAC) survey and a new total score (NAC-3).

Methods: Comparisons were made to existing caregiver quality of life, distress, and burden instruments through an online, cross-sectional survey of U.

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Background: Despite recommendations and policies to integrate family caregivers into U.S. healthcare settings, caregivers are not systematically involved.

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Background: Asian American women face disproportionate burden of cervical cancer (CC) than non-Hispanic white women in the U.S. The goal of this study was to assess the feasibility and impact of a culturally tailored intervention to promote Human papillomavirus (HPV) self-sampling test among hard-to-reach Asian American women.

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Background: There is extensive interest in understanding how neighborhood socioeconomic status (nSES) may affect cancer incidence or survival. However, variability regarding items included and approaches used to form a composite nSES index presents challenges in summarizing overall associations with cancer. Given recent calls for standardized measures of neighborhood sociodemographic effects in cancer disparity research, the objective of this systematic review was to identify and compare existing nSES indices studied across the cancer continuum (incidence, screening, diagnosis, treatment, survival/mortality) and summarize associations by race/ethnicity and cancer site to inform future cancer disparity studies.

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Background: Most safety and efficacy trials of the SARS-CoV-2 vaccines excluded patients with cancer, yet these patients are more likely than healthy individuals to contract SARS-CoV-2 and more likely to become seriously ill after infection. Our objective was to record short-term adverse reactions to the COVID-19 vaccine in patients with cancer, to compare the magnitude and duration of these reactions with those of patients without cancer, and to determine whether adverse reactions are related to active cancer therapy.

Patients And Methods: A prospective, single-institution observational study was performed at an NCI-designated Comprehensive Cancer Center.

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Healthcare employees often experience high stress and may benefit from accessible psychosocial interventions. In this pilot study, we explored preliminary feasibility, acceptability, and psychological effects of a telephone-based adaption of mindfulness-based stress reduction (MBSR) for healthcare employees. Eleven participants (M age = 49.

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