Publications by authors named "Caroll A Webers"
Objective: Recent studies have examined retinal vascular abnormalities in schizophrenia as retinal vascular imaging is a non-invasive proxy to cerebral microvasculature. However, relation between retinal vascular abnormalities and brain structure is not well examined in schizophrenia. Hence in this study, for the first time, we examined the relationship between retinal vascular measures and brain white matter lesions in schizophrenia.
View Article and Find Full Text PDFBackground And Objectives: Higher serum phosphate is associated with cardiovascular events and all-cause mortality. Explanations of this association have focused on large vessel calcification and stiffness. Studies suggest that a higher serum phosphate induces microvascular dysfunction, but relationships in humans with direct measures of microvascular function are lacking.
View Article and Find Full Text PDFArticle Synopsis
- * Comprehensive eye examinations and next-generation sequencing (NGS) identified specific mutations in the CHM gene, which were confirmed in both families, with asymptomatic family members identified as carriers.
- * The findings highlight how these genetic mutations impact retinal health, leading to abnormalities due to diminished production of Rab escort protein-1 (REP-1), which is crucial for retinal function.