Direct medical and non-medical costs of a one-year care pathway for early operable breast cancer: Results of a French multicenter prospective study.

Introduction: The organization of health care for breast cancer (BC) constitutes a public health challenge to ensure quality of care, while also controlling expenditure. Few studies have assessed the global care pathway of early BC patients, including a description of direct medical costs and their determinants. The aims of this multicenter prospective study were to describe care pathways of BC patients in a geographic territory and to calculate the global direct costs of early stage BC during the first year following diagnosis.

What every radiologist should know about adnexal torsion.

Adnexal torsion is the fifth most common gynecologic surgical emergency, requiring clinician and radiologist awareness. It involves the rotation of the ovarian tissue on its vascular pedicle leading to stromal edema, hemorrhagic infarction, and necrosis of the adnexal structures with the subsequent sequelae. Expedient diagnosis poses a difficult challenge because the clinical presentation is variable and often misleading.

Preoperative clinical pathway of breast cancer patients: determinants of compliance with EUSOMA quality indicators.

Background: The European Society of Breast Cancer Specialists (EUSOMA) has defined quality indicators for breast cancer (BC). The aim of this study was to describe the preoperative clinical pathway of breast cancer patients and evaluate the determinants of compliance with EUSOMA quality indicators in the Optisoins01 cohort.

Methods: Optisoins01 is a prospective, multicentric study.

The patient-breast cancer care pathway: how could it be optimized?

Background: A care pathway is defined as patient-focused global care that addresses temporal (effective and coordinated management throughout the illness) and spatial issues (treatment is provided near the health territory in or around the patient's home). Heterogeneity of the care pathways in breast cancer (BC) is presumed but not well evaluated. The OPTISOINS01 study aims to assess every aspect of the care pathway for early BC patients using a temporal and spatial scope.

[Diagnosis of cervical and endometrial cancer].

Updated French guidelines for clinical practice have been published by the National Cancer Institute in 2010, concerning the diagnosis and the treatment of cervix and endometrial cancers. The diagnosis of cervix cancer, suspected when a cervix tumour is observed in a patient presenting with vaginal bleeding, especially in women with risk factors (previous cervix dysplasia, HIV infection, tobacco use). The diagnosis is confirmed by pathology of cervix biopsy (macroscopic cervix tumour or microscopic lesions detected by screening).

[Menometrorrhagia].

Menometrorrhagia is a frequent cause of medical consulting. After exclusion of pregnancy, main aetiologies are the uterine (polyp, myoma, adenomyosis, cancer) or adnexial abnormality (ovarian cyst or cancer), the disorders of hemostasis (Willebrand..

Combined conservative surgical and medical treatment of a uterocutaneous fistula.

Uterocutaneous fistula is a rare complication that may follow cesarean section. Herein is described a rare case of uterocutaneous fistula. The patient, a 28-year-old woman with a history of American Society for Reproductive Medicine stage IV endometriosis (Douglas pouch obliteration), underwent a cesarean section at 25 weeks of gestation (twin pregnancy).

Surgical reduction of hypertrophy of the labia minora.

Objective: To evaluate postoperative satisfaction, including improvements in quality of life, among patients who had undergone labia minora reduction.

Methods: In a retrospective descriptive study, women who had undergone labiaplasty for hypertrophy of the labia minora between January 2005 and December 2009 were contacted by telephone. The women were asked to answer a satisfaction survey evaluating the esthetic and functional results of the surgery.

Doxorubicin and ifosfamide for high-grade sarcoma during pregnancy.

Purpose: Doxorubicin and ifosfamide are highly active drugs for the treatment of high-grade sarcomas, but little is known on the optimal management of young patients who develop such malignancies during pregnancy.

Methods: We report on a single-institution series of patients (n = 9) with high-grade sarcoma diagnosed during the third trimester of pregnancy. Neoadjuvant chemotherapy combining doxorubicin (50 mg/m(2) day 1) and ifosfamide (2.

Fertility after B-Lynch suture and stepwise uterine devascularization.

Objective: To report the obstetric outcome in a patient who had previously undergone a stepwise uterine devascularization followed by a B-Lynch suture for severe postpartum hemorrhage (PPH).

Design: Case report.

Setting: University hospital.

Fertility and pregnancy outcomes following uterine devascularization for severe postpartum haemorrhage.

Background: To evaluate the fertility and pregnancy outcomes following uterine devascularization for postpartum haemorrhage (PPH).

Methods: All patients who required uterine devascularization, i.e.