Publications by authors named "Caroline Stadelmann"
Introduction: Vaginal progesterone supplementation is frequently given to patients receiving frozen embryo transfer (FET) in the natural cycle aiming to increase the chance of pregnancy and live birth. To date, only a few studies have investigated if progesterone supplementation is beneficial in these cycles and the level of evidence for progesterone supplementation is very low.
Methods And Analysis: The ProFET trial is a multicentre, open-label, randomised controlled trial powered for this investigation, including 1800 women with regular menstrual cycles (24-35 days), aged 18-43 years planned for natural cycle-FET receiving a single blastocyst for transfer.
Article Synopsis
- - The study investigated whether endometrial scratching, a technique used to enhance embryo implantation, could increase pregnancy rates in women undergoing in vitro fertilization (IVF).
- - Over 1,300 women were randomly assigned to either the endometrial scratching group or a control group with no intervention, and the primary outcome measured was the rate of live births.
- - Results showed no significant difference in live birth rates between the two groups (26.1% in both), and the pain from the scratching procedure was reported to be moderate.