Publications by authors named "Caroline Simonis"

Article Synopsis
  • Unilateral labyrinthectomy (UL) in rodents leads to a complex motor syndrome characterized by both circling and rolling in the acute stage, but only circling persists in the chronic stage due to compensation from proprioceptive information.
  • Dopaminergic lesions in both 6-OHDA and apomorphine-treated rats also result in circling behaviors, indicating a similarity in motor deficits caused by vestibular and dopaminergic system disruptions.
  • Two hypotheses explain these behaviors: one suggests a shared three-dimensional control by both systems, while the other posits that the dopaminergic network manages postural control specifically in one plane, explaining why barrel rolling is absent in dopaminergic lesion cases.
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A common problem in the quantification of the orientation of the femoral neck is the difficulty to determine its true axis; however, this axis is typically estimated visually only. Moreover, the orientation of the femoral neck is commonly analysed using angles that are dependent on anatomical planes of reference and only quantify the orientation in two dimensions. The purpose of this study is to establish a method to determine the three-dimensional orientation of the femoral neck using a three-dimensional model.

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In traditional as well as in geometric morphometric studies, the shape of the pelvis is often quantified after the reassembly of the two hip bones and the sacrum. However, on dry bones, the morphology of the cartilaginous tissues that form the two sacroiliac joints and the pubic symphysis before death remains unknown, leading to potential inaccuracies and errors during the reassembly process. A protocol was established to investigate the effects of reassembly on the quantification of pelvis shape.

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The developing fetus is protected from external environmental influences by maternal tissues. However, these structures have a limited elasticity, such that the fetus must grow in a confined space, constraining its size at the end of pregnancy. Can these constraints modify the morphology of the fetal skeleton? The intensity of these constraints increases between 5 months and birth, making it the most appropriate period to address this question.

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