Publications by authors named "Caroline Shadowen"

Anti-NMDA receptor (A-NMDAR) encephalitis is an autoimmune condition often associated with ovarian teratoma. Surgical removal of the teratoma is generally curative, and recurrence is uncommon. A 14-year-old female presented with psychiatric symptoms and was ultimately diagnosed with A-NMDAR encephalitis during a prolonged hospitalization.

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Article Synopsis
  • Herpes simplex (HSV) and varicella zoster (VZV) are serious concerns during pregnancy due to their potential to harm both mother and baby through direct infection and complications.
  • A case involving a 19-year-old pregnant woman with VZV symptoms was successfully treated with acyclovir, leading to a healthy delivery.
  • It is crucial to investigate genital lesions for VZV in pregnant patients, especially those lacking immunity, to develop effective management and ensure safety for mother and baby during childbirth.
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Introduction: Opioid use disorder (OUD) is a leading cause of pregnancy-associated deaths. OUD treatment with buprenorphine (BUP) reduces overdose risk and improves perinatal outcomes. Incarceration can be a barrier to receipt of OUD treatment during pregnancy and postpartum.

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Article Synopsis
  • Opioid overdoses are a significant cause of pregnancy-related deaths, especially within the first year after giving birth, prompting a study on recovery for postpartum women in treatment for opioid use disorder.
  • This mixed-methods research involved women 2-6 months postpartum from a perinatal addiction clinic, utilizing surveys and interviews to explore their definitions of recovery and related experiences.
  • Participants viewed recovery as a transformative process focused on personal growth, resilience, and various life improvements, with medication for opioid use disorder playing a crucial role in their recovery journey.
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Objectives: For women with opioid use disorder (OUD), the postpartum period is an especially vulnerable period. Buprenorphine (BUP) improves OUD outcomes during this timeframe. Once-monthly injectable BUP (XRI-BUP) is a newer formulation for which evidence of use in postpartum women is extremely limited.

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Background: Knowledge of medical conditions and their evidence-based medications varies among individuals. This range of knowledge may affect attitudes and influence medical decision-making of both patients and providers. Perceptions may be even more impactful in pregnancy, a timeframe subject to bias, and in diseases that include behavioral symptoms and often carry significant societal stigma, such as opioid use disorder (OUD).

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Purpose Of Review: Opioid-related deaths are a leading cause of mortality during pregnancy through 12 months postpartum. Buprenorphine use during pregnancy is increasing, yet expert opinion on its dosing through the perinatal period is limited. We provide a review of the current clinical literature on buprenorphine dosing during pregnancy through 12 months postpartum.

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Synopsis of recent research by authors named "Caroline Shadowen"

  • - Caroline Shadowen's recent research focuses on complex medical issues related to women's health, particularly in pregnancy and postpartum settings, including opioid use disorder and autoimmune conditions.
  • - Her work highlights critical case studies, such as the intersection of recurrent anti-NMDAR encephalitis and oophorectomy in adolescent patients, as well as the implications of infections like genital VZV during pregnancy.
  • - Shadowen emphasizes the importance of interdisciplinary care and patient-provider knowledge in managing complications, with a particular interest in optimizing treatment outcomes for postpartum women facing opioid use disorder.