Publications by authors named "Caroline S Monk"
Purpose: Tetracyclines have activity against matrix metalloproteinases (MMP). Oral medications with effects on the ocular surface are of interest in patients where repeated topical dosing is limited. The aim of this study was to characterize the concentration of minocycline in the tears of normal horses after oral administration and to determine if this level directly inhibits MMP activity.
View Article and Find Full Text PDFObjective: To measure intraocular pressure (IOP) in horses during hoisting after induction of anesthesia.
Study Design: Prospective nonrandomized clinical study.
Animals: Eighteen healthy adult horses aged [mean±standard deviation (SD)] 10±4.
The objective of this paper is to describe clinical behavior, histopathologic features, and immunohistochemical staining of two-related horses with intraocular teratoid medulloepithelioma. Two-related Quarter Horses with similar intraocular masses presented to the UF-CVM Comparative Ophthalmology Service for evaluation and treatment. The first horse, a 3-year-old gelding, had glaucoma and a cyst-like mass in the anterior chamber.
View Article and Find Full Text PDFObjective: To determine serum and tissue concentrations of gallium (Ga) after oral administration of gallium nitrate (GaN) and gallium maltolate (GaM) to neonatal calves.
Animals: 8 healthy neonatal calves.
Procedures: Calves were assigned to 1 of 2 groups (4 calves/group).
Objective: To determine whether cortisol is present in equine tears at rest and during simulated stress and compare tear cortisol to serum free and total cortisol.
Materials And Methods: Fourteen healthy adult horses were included. Paired tear total cortisol and serum total and free cortisol concentrations were measured with ELISA, chemiluminescent immunoassay, and ultrafiltration methodology, respectively, in 10 horses at rest once daily for five consecutive days.