Publications by authors named "Caroline Os Savage"
JCI Insight
December 2020
Article Synopsis
- This study focuses on the role of small noncoding RNAs, specifically miRNAs, in kidney disease, exploring their potential as biomarkers for diagnosing and monitoring disease progression and treatment efficacy.*
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- Researchers utilized a cell-specific small RNA sequencing approach to analyze various cell types in injured and repairing kidneys, leading to the creation of a comprehensive miRNA catalog that maps changes during kidney injury and recovery.*
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- The team identified specific miRNAs, particularly miR-16-5p and miR-18a-5p, that are enriched in macrophages and found these miRNAs to be promising urinary biomarkers for acute kidney injury in transplant patients.*
