Diagnostic use of neuro-spect quantified with Tc-ECD a model based on normal data.

Objective: The purpose of the present study was to prospectively quantify the normal limits of brain perfusion using specific software in a group of asymptomatic young volunteers submitted to single-photon emission tomography (SPECT) with Tc-ethyl cysteinate dimer (Tc-ECD).

Methods: We used 15 MBq/kg of intravenous Tc-ECD in 30 healthy volunteers submitted to brief neuropsychological tests and a clinical questionnaire. These data were normalized relative to the cerebellum (Group 1) and to the brain cortex (Group 2).