Publications by authors named "Caroline Monnard"
Steady hematopoiesis is essential for lifelong production of all mature blood cells. Hematopoietic stem and progenitor cells (HSPCs) found in the bone marrow ensure hematopoietic homeostasis in an organism. Failure of this complex process, which involves a fine balance of self-renewal and differentiation fates, often result in severe hematological conditions such as leukemia and lymphoma.
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- Developed a new ICP-MS method for analyzing 20 elements in 10 μL of serum and 12 elements in under 250,000 cells, making it reliable and easy to use.
- Conducted proof-of-concept studies that revealed noticeable differences in elemental profiles between serum and immune T cells from naı̈ve versus tumor-bearing mice.
- This research opens up new possibilities for studying rare cell populations and small biofluid samples, providing insights into the role of elements in biological and disease processes.
The intake of adequate amounts and types of nutrients is key for sustaining health and a good quality of life, particularly in the elderly population. There is considerable evidence suggesting that physiological changes related to age and sex modify nutritional needs, and this may be related to age-associated changes in body composition (BC), specifically in lean and fat body mass. However, there is a clear lack of understanding about the association of nutrients in blood and BC parameters in the elderly.
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