Publications by authors named "Caroline Meers"
Purpose: To evaluate the feasibility of robot-assisted retinal vein cannulation for retinal vein occlusion.
Methods: Prospective experimental study performed in in vivo porcine eyes. A standard three port pars plana vitrectomy was followed by laser-induced branch retinal vein occlusion.
Purpose: To develop a methodology for cannulating porcine retinal venules using a robotic assistive arm after inducing a retinal vein occlusion using the photosensitizer rose bengal.
Methodology: Retinal vein occlusions proximal to the first vascular branch point were induced following intravenous injection of rose bengal by exposure to 532nm laser light delivered by slit-lamp or endolaser probe. Retinal veins were cannulated by positioning a glass catheter tip using a robotically controlled micromanipulator above venules with an outer diameter of 80μm or more and performing a preset piercing maneuver, controlled robotically.
Article Synopsis
- PEEK materials, used in orthopedic surgery, face challenges in bone adhesion due to their low biocompatibility, prompting this study to investigate the impact of titanium and calcium phosphate (CaP) coatings on bone tissue adhesion.
- In a study with six adult sheep, three types of PEEK dowels were implanted: uncoated (control), with CaP coating, and with titanium coating, and then analyzed after different time intervals.
- The results showed that titanium-coated PEEK dowels had significantly greater bone implant contact and bone volume compared to uncoated dowels, indicating that titanium coating enhances the adhesion of bone tissue to these implants.
Background: Donor lungs are susceptible to aspiration in the period before and after brain death. We hypothesized that preemptive anti-inflammatory treatment may result in better graft performance as evaluated during ex vivo lung perfusion (EVLP).
Methods: Pigs (27.
Background: Evidence of aspiration remains a major reason for declining donor lungs contributing to current organ shortage. The aim of the present ex vivo lung perfusion (EVLP) study was to compare lungs injured by gastric juice (GJ) with normal lungs.
Methods: Pigs (32.
Background: About 15% of donor lungs are declined because of aspiration contributing to current organ shortage. The aim was to develop a porcine lung injury model by gastric juice (GJ) instillation to study different pretransplant treatment strategies.
Materials And Methods: Pigs (n = 6/group) were anesthetized and monitored.
Relaxing the standard lung donor criteria may significantly increase the reported 15% organ yield but post-transplant recipient outcome should be carefully monitored. Charts from all consecutive deceased organ donors within our hospital network were reviewed over a 2-year period. Reasons for lung refusals and number of lungs transplanted were analysed.
View Article and Find Full Text PDFBackground: Brain death rapidly results in lung injury making many cadaveric donors unsuitable for lung transplantation. The aim of this study was to develop a porcine model of lung injury as a first step to study mechanisms to ameliorate the pretransplant graft quality during ex vivo perfusion.
Materials And Methods: Male pigs (47 ± 8 kg) were divided into three groups: LPS-group [LPS] (n = 6) [instillation of lipopolysaccharides (15 mg/lung)]; saline-group [SAL] (n = 5) (50 mL saline/lung); and sham-group [SHAM] (n = 5).
Background: The use of non-heart-beating donors (NHBD) to overcome organ shortage is moving into the clinic. In 2007, 5 of 51 lung transplantations (LTx) in our center were performed with lungs from controlled NHBD.
Methods: Our aim was to describe these 5 NHBD LTx recipients and compare early outcome (