Publications by authors named "Caroline Mary Gurgel Dias Florencio"

Background: To analyse the temporal trends and spatiotemporal distribution of leprosy relapse in Brazil from 2001 to 2021.

Methods: An ecological study with a temporal trend approach and space-time analysis of leprosy relapse in Brazil was carried out with data from the Notifiable Diseases Information System.

Results: A total of 31 334 patients who experienced leprosy relapse were identified.

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Article Synopsis
  • * Key risk factors for higher mortality include being elderly, black, experiencing jaundice and edema, and not taking prescribed medication, while treatment with pentavalent antimonial significantly reduces the risk of death.
  • * The findings suggest that improving understanding of these risk factors can enhance public health policies and epidemiological surveillance to prevent HVL-related deaths.
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  • Human visceral leishmaniasis (HVL) is a significant health concern in Ceará, Brazil, which has high rates of incidence and mortality related to the disease from 2007 to 2021.
  • The study analyzed data from a notifiable diseases information system, revealing peak incidences in 2009 and 2011, along with notable mortality rates concentrated primarily in 2011.
  • Results showed that specific municipalities, particularly in the Northern, Northwestern, and Southern areas of Ceará, faced the highest risks of HVL, indicating a persistent endemic situation throughout the study period.
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Visceral leishmaniasis (VL) is considered as an important tropical disease because it rapidly spreads across a wide geographical area. This study aimed to analyse the temporal and spatial patterns of incidence, mortality and case fatality rates due to human VL in Ceará, Brazil, from 2007 to 2018. This is an ecological study involving time series and spatial analyses, and data were obtained from human VL notifications.

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  • The study focused on leprosy relapse cases in Ceará from 2001 to 2018, analyzing their trends and prevalence.
  • A total of 1,777 relapse cases were identified, with higher rates among men, illiterate individuals, those of mixed race, and those with specific types of leprosy or visible disabilities.
  • The data indicated a rising trend in leprosy relapse over the study period, highlighting the ongoing challenges in managing the disease in vulnerable populations.
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Objective: To analyze the temporal trend and describe the spatial distribution of Visceral Leishmaniasis (VL) in Fortaleza from 2007 to 2017.

Methods: This was an ecological study using segmented temporal regression and thematic mapping.

Results: Between 2007-2017, 1,660 new cases and 97 deaths were confirmed.

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Article Synopsis
  • Visceral leishmaniasis, a deadly disease caused by the Leishmania parasite and primarily transmitted by sandflies, is endemic in Ceara State, Brazil, where dogs serve as the main reservoir.
  • The study analyzed human visceral leishmaniasis (HVL) cases in Ceara from 2003 to 2017, revealing it mainly affects urban males, particularly children under five and young adults aged 30-49.
  • Findings show a concerning trend of increasing incidence and mortality rates, along with a geographic expansion of the disease throughout the region.
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  • - The study examined the distribution of inappropriate post-exposure human rabies treatments in Ceará, Brazil from 2007 to 2015, using data from a disease notification system.
  • - Analyzing 222,036 records showed that a significant 95.8% were inappropriate, displaying uneven spatial distribution with notable clusters in the northeast and northwest regions.
  • - The results aim to inform targeted strategies to minimize unnecessary rabies treatment procedures in the future.
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