Excision of an intrascleral cyst guided by anterior segment optical coherence tomography.

A 4-year-old girl presented with an enlarging, congenital, intrascleral cyst of the left eye. Intraoperative anterior segment optical coherence tomography was used to visualize and to assess the extent of the cyst, facilitating safe excision. The cyst was completely removed, and the defect was covered with an amniotic membrane graft, with a good outcome.

Conjunctival Squamous Cell Carcinoma with Corneal Stromal Invasion in Presumed Pterygia: A Case Series.

Aim: To describe 4 cases of conjunctival squamous cell carcinoma (SCC) with corneal stromal invasion.

Methods: Retrospective, clinicopathologic case series.

Results: All patients had prior resections of presumed pterygia.

Gene Expression Profiling and Heterogeneity of Nonspecific Orbital Inflammation Affecting the Lacrimal Gland.

Importance: Although a variety of well-characterized diseases, such as sarcoidosis and granulomatosis with polyangiitis, affect the lacrimal gland, many patients with dacryoadenitis are diagnosed as having nonspecific orbital inflammation (NSOI) on the basis of histology and systemic disease evaluation. The ability to further classify the disease in these patients should facilitate selection of effective therapies.

Objective: To test the a priori hypothesis that gene expression profiles would complement clinical and histopathologic evaluations in identifying well-characterized diseases and in subdividing NSOI into clinically relevant groups.

Giant Chondroid Syringoma of the Lower Eyelid.

Chondroid syringoma is a benign mixed tumor characterized by sweat gland elements in a cartilaginous stroma. This rare tumor accounts for only 0.01% of all primary skin tumors and occurs only rarely in the periorbital region.