Publications by authors named "Caroline M BrandAo"
Background: Mohs micrographic surgery is worldwide used for treating skin cancers. After obtaining tumor-free margins, choosing the most appropriate type of closure can be challenging.
Objectives: Our aim was to associate type of surgical reconstructions after Mohs micrographic surgery with the characteristics of the tumors as histological subtype, anatomical localization and especially number of surgical stages to achieve complete excision of the tumour.
Background/aim: Non-melanoma skin cancer (NMSC) is the most prevalent type of cancer in adults. Surgery remains the golden-standard treatment for this disease. Mohs micrographic surgery (MMS), a surgical technique, is based on the three-dimensional histopathological examination of the margin and surgical bed, layer by layer, in the excised tissue allowing for the determination of the location of the residual tumor, for its complete excision, with high cure rates and preservation of the unaffected tissue.
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- - Lacaziosis, a disease with unclear origins, has been studied for its immune response at both the systemic and dermal levels, highlighting a variety of immune cells involved in the inflammatory process.
- - Research indicates that lacaziosis lesions typically feature macrophages and various T cells, natural killer cells, and B lymphocytes, suggesting a complex immune response.
- - A case study of a 54-year-old man from the Brazilian Amazon revealed long-term lesion progression and showed that the dermal immune response varies by lesion type, revealing specific immune cells and cytokine profiles.