An incidental finding of a nodal recurrence of cutaneous malignant melanoma after a 45-year disease-free period.

We report the case of an 84-year-old woman who had a nodal recurrence of melanoma 45 years after the primary diagnosis of an extremity cutaneous melanoma. It is believed to be the longest disease-free latency period reported between primary melanoma diagnosis and recurrence to date. Late recurrences of melanoma are rare and recurrence after four decades extremely rare.

Adolescent idiopathic scoliosis in Down's syndrome.

Adolescent idiopathic scoliosis in Down's syndrome individuals has previously been reported in the context of institutionalised individuals and is of an iatrogenic nature, resulting from previous thoracotomy for congenital heart defects. We report the case of a male, non-institutionalised Down's syndrome individual, with no history of previous thoracic surgery and we follow the natural history of the condition, with particular reference to height velocity and curve progression velocity throughout puberty and successful treatment with a Boston thoracolumbosacral orthosis.