Publications by authors named "Caroline Kremer"
Objectives: Spinal cord stimulation (SCS) therapy is an effective treatment for chronic pain, particularly in conditions such as postlaminectomy syndrome and complex regional pain syndrome (CRPS). Rare case reports described significant weight loss in patients who underwent dorsal column SCS therapy for chronic pain. Recently, neuromodulation for obesity has become a novel field for research.
View Article and Find Full Text PDFParvalbumin-expressing inhibitory neurons (PVNs) stabilize cortical network activity, generate gamma rhythms, and regulate experience-dependent plasticity. Here, we observed that activation or inactivation of PVNs functioned like a volume knob in the mouse auditory cortex (ACtx), turning neural and behavioral classification of sound level up or down over a 20dB range. PVN loudness adjustments were "sticky", such that a single bout of 40Hz PVN stimulation sustainably suppressed ACtx sound responsiveness, potentiated feedforward inhibition, and behaviorally desensitized mice to loudness.
View Article and Find Full Text PDFArticle Synopsis
- Ethmoidal dural arteriovenous fistulas (dAVFs) pose treatment challenges due to their complex structure, and traditional surgical methods often lead to noticeable scarring; this study explores a minimally invasive approach using an eyelid incision.
- The study analyzed 6 patients who underwent surgery via a blepharoplasty incision, achieving 100% success in disconnecting the dAVFs without any serious complications; most issues were minor and self-resolving.
- The transpalpebral approach offers not only effective treatment with improved cosmetic outcomes but also enhanced access for surgeons, making it a promising option for managing ethmoidal dAVFs.