Publications by authors named "Caroline Gorbatchef"

Background: The main concerns following sleeve gastrectomy (SG) include the risk of gastroesophageal reflux disease (GERD) and its complications, such as Barrett's esophagus (BE). However, there is conflicting data on esophageal conditions, and studies on alterations of gastric mucosa after SG are lacking, despite reported cases of gastric cancer. Our aim was to assess esophageal and gastric lesions after SG.

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Background And Aims: There has been interest in the use of pyloric therapies for the treatment of refractory gastroparesis. However, data on endoscopic pyloric dilation are scarce. We aimed to assess the efficacy and safety of this procedure in refractory gastroparesis.

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Article Synopsis
  • The study investigated the changes in gastroesophageal reflux disease (GERD) symptoms in 160 patients one year after undergoing sleeve gastrectomy (SG) and aimed to identify preoperative predictive factors.* -
  • Results indicated that while about 36.3% of patients reported GERD symptoms after surgery, some experienced improvements, and 29.6% of those who were initially asymptomatic developed new symptoms.* -
  • The only significant predictors of postoperative GERD symptoms were preoperative GERD symptoms and positive preoperative ambulatory pH monitoring in asymptomatic patients, rather than other factors like manometric measurements or weight loss.*
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Background: Oesophageal radiofrequency reduces use of proton pump inhibitors (PPIs) in patients with gastro-oesophageal reflux disease responding to PPIs.

Aim: To determine the efficacy of oesophageal radiofrequency in patients with PPI-refractory heartburn.

Methods: A randomised, double-blind, sham-controlled multicentre study was designed to assess the efficacy of oesophageal radiofrequency in PPI non-responding patients with heartburn.

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Background/aims: Jackhammer esophagus (JE) is a hypercontractile esophageal motor disorder defined by at least two swallows with a distal contractile integral (DCI) >8000 mm Hg.s.cm during high-resolution manometry (HRM).

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Background: Evolution of gastroesophageal reflux disease (GERD) after sleeve gastrectomy (SG) is controversial. Some authors report worsening or improvement of preoperative GERD, others the occurrence of de novo GERD between 5 and 69%.

Aims: The aims of this study are to evaluate the evolution of GERD after SG by ambulatory 24-h pH monitoring (APM) and to determine pre- and postoperative clinical and manometric factors associated with its evolution.

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