A Systematic Review of the Diagnostic Value of CT Imaging in Diagnosing Otosclerosis.

Objective: To evaluate the diagnostic value of computed tomography (CT) in detecting otosclerosis in patients with conductive hearing loss and a clinical suspicion of otosclerosis.

Data Sources: PubMed, Embase, and the Cochrane Library.

Study Selection: A systematic search was conducted.

Estrogen augmentation in schizophrenia: a quantitative review of current evidence.

Background: Sex differences in the incidence, onset and course of schizophrenia have led to the hypothesis that estrogens play a protective role in the pathophysiology of this disorder. Several trials have assessed the potential of estrogens in reducing schizophrenia symptoms, showing inconsistent results. This quantitative review summarizes available evidence on the efficacy of estrogens in the treatment of schizophrenia.