Publications by authors named "Caroline Conci Campos"
Article Synopsis
- Polymyxins are used as a last-resort treatment for infections caused by resistant Gram-negative bacteria, specifically targeting Klebsiella pneumoniae in this study.
- The study analyzed 97 strains of K. pneumoniae for resistance mechanisms, identifying key β-lactamase genes and mutations in the pmrB gene associated with polymyxin resistance.
- Findings show high prevalence of specific resistance genes and confirm that mutations in pmrB, particularly T157P, are significant in developing resistance among the K. pneumoniae strains in Brazilian public hospitals.
Introduction: Infections caused by multidrug-resistant Klebsiella pneumoniae are difficult to treat and pose a serious threat to public health worldwide. Here, we describe the presence of carbapenemase-producing K. pneumoniae in intensive care units (ICU) of three major Mato Grosso do Sul hospitals located in the Midwest region of Brazil.
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