Publications by authors named "Caroline Biazzolo Zancan"
Article Synopsis
- - Oral cancer (OC) is often diagnosed late due to its lack of early symptoms and distinctive signs, leading to treatment challenges and poorer outcomes, highlighting the need for better early detection methods, particularly through salivary cytokines (SC) as potential biomarkers.
- - The study systematically reviewed literature from PubMed and Cochrane Library, focusing on case-control studies measuring SC in saliva of treatment-naïve patients, to evaluate their use as diagnostic tools for OC.
- - Results from 28 studies indicated that specific SC levels, especially IL-8 and IL-6, were significantly higher in OC patients compared to healthy individuals and those with other oral conditions, suggesting a potential for these cytokines in the early diagnosis of oral
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