Prognostic role of SOX2 and STAT3 expression on circulating T lymphocytes and CD44+/CD24 cells in the locally advanced and metastatic breast cancer.

Background: Breast cancer (BC) is associated with a continuous increase in incidence, with high mortality rates in several countries. CD44, STAT3, and SOX2 are related to regulating of somatic cell division, tumorigenesis, and metastasis in BC.

Methods: A cross-sectional study was carried out at the Hospital de Cancer de Pernambuco (HCP) between 2017 and 2018.