Publications by authors named "Carolina U Stahler"
Physiol Behav
January 2025
Article Synopsis
- Several mechanisms of Parkinson's disease (PD) are unclear, and current treatments are ineffective; however, a process called SUMOylation might offer new benefits.
- Researchers knocked down a specific protein (SENP3) in a rodent model, increasing SUMO-2/3 conjugation, and observed improvements in cognitive and motor functions after MPTP exposure.
- The study suggests that enhancing SUMO-2/3 conjugation could be a promising therapeutic approach to address the cognitive and motor difficulties associated with PD.
