The influence of sleep quality on the development of periocular hyperchromia: a case-control study.

Background: Periorbital hyperchromia (POH), popularly known as "dark circles," is a very frequent complaint in dermatological appointments. It affects all phototypes, genders, and ages, and it is associated with a tired and aged aspect to the face, which may lead to esthetic concerns and impairments in the quality of life. Its etiology is multifactorial, and it is believed that sleep disorders may be considered as precipitating or aggravating factors.

Association between clinical characteristics, quality of life, and sleep quality in patients with periorbital hyperchromia.

Introduction: Periorbital hyperchromia (POH) is a multifactorial condition, precipitated or aggravated by sleep disorders, which negatively affects quality of life (QoL). The aim of this study was to evaluate the impact of POH on QoL, sleep quality, and dissatisfaction of affected patients.

Methods: In this cross-sectional study of male and female patients over 18 years, participants were examined, their demographic data were registered, and Dermatology Quality of Life Index (DLQI), Pittsburgh Sleep Quality Index (PSQI-BR), and Visual Analogue Scale (VAS) were used to assess dissatisfaction.

Hirsutism in Polycystic Ovary Syndrome: Pathophysiology and Management.

Background: Hirsutism is defined as the presence of terminal hair with male distribution in women, and polycystic ovary syndrome (PCOS) is the most common etiology of hirsutism.

Methods: The aim of this study is to review aspects of hair growth that are relevant for the understanding of hirsutism in PCOS, along with current treatment alternatives.

Results: The prevalence of hirsutism in PCOS ranges from 70 to 80%, vs.

Incidence and endoscopic characteristics of acute laryngeal lesions in children undergoing endotracheal intubation.

Introduction: Acute laryngeal lesions after intubation appear to be precursors of chronic lesions.

Objective: To describe the incidence and type of acute laryngeal lesions after extubation in a pediatric intensive care unit (PICU).

Methods: A cohort study involving children from birth to <5 years, submitted to intubation for more than 24h in the PICU of an university hospital.

A double-blind, randomised, crossover trial of two botulinum toxin type a in patients with spasticity.

Background: Botulinum toxin type A (btxA) is one of the main treatment choices for patients with spasticity. Prosigne® a new released botulinum toxin serotype A may have the same effectiveness as Botox® in focal dystonia. However, there are no randomized clinical trials comparing these formulations in spasticity treatment.

Effect of turbinate surgery in rhinoseptoplasty on quality-of-life and acoustic rhinometry outcomes: a randomized clinical trial.

Objectives/hypothesis: To evaluate the role of inferior turbinate reduction during rhinoseptoplasty in quality-of-life outcomes and nasal airway cross-sectional area.

Study Design: Randomized clinical trial.

Methods: Individuals over 16 years with nasal obstruction, candidates to functional and aesthetics primary rhinoseptoplasty, were evaluated from December 2010 though January 2012 at a tertiary University Hospital, Brazil.