Publications by authors named "Carolina Maria Medeiros do Amaral"

Article Synopsis
  • Lung cancer is the leading cause of cancer deaths globally, with a significant portion of cases occurring in non-smokers, highlighting the complexity of its risk factors beyond tobacco.
  • Factors contributing to lung cancer in non-smokers include exposure to diesel exhaust, metals, radiation, radon, air pollution, and potentially infectious agents like human papillomavirus (HPV).
  • The review explores how HPV may interact with lung tissues, focusing on the molecular mechanisms of its protein activity and the possible pathways through which HPV might enter lung cells.
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The aim of this study was to examine the prevalence and genetic variability of the capsid L1 gene of rare HPV genotypes that were found in the cervical lesions of women from North-East Brazil. A total number of 263 patients were included in this study. HPV detection was performed using PCR followed by direct sequencing of MY09/11, as well as type-specific PCR to detect the Alpha-9 species.

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Cervical cancer is the second most common cancer in females worldwide. It is well-established that Human Papillomavirus (HPV) infections play a critical role in the development of cervical cancer. However, a large number of women infected with oncogenic HPV types will never develop cervical cancer.

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