Gender differences in the effect of diabetes mellitus and its treatment on osteoarthritic pain.

Objective: (1) To investigate differences in pain severity and its distribution between patients with and without diabetes mellitus (DM) in a population with advanced osteoarthritis (OA). (2) To explore the role of medication used for diabetes in these associations.

Research Design And Methods: This is a hospital-based cohort study of patients with advanced OA requiring total joint arthroplasty.