Does active Crohn's disease have decreased intestinal antioxidant capacity?

Background And Aims: Oxidative stress is presumed to play an important role in Crohn's disease (CD) pathogenesis. Nevertheless, the evaluation of the intestinal antioxidant capacity through the analysis of glutathione peroxidase activity in CD remains to be determined.

Methods: 20 CD outpatients and 16 volunteers going through colonic cancer screening were enrolled.