Publications by authors named "Carolina Gonzaga Carvalho"
Objective: Despite evidence of a relationship among obstructive sleep apnea (OSA), metabolic dysregulation, and diabetes, it is uncertain whether OSA treatment can improve metabolic parameters. We sought to determine effects of long-term continuous positive airway pressure (CPAP) treatment on glycemic control and diabetes risk in patients with cardiovascular disease (CVD) and OSA.
Research Design And Methods: Blood, medical history, and personal data were collected in a substudy of 888 participants in the Sleep Apnea cardioVascular Endpoints (SAVE) trial in which patients with OSA and stable CVD were randomized to receive CPAP plus usual care, or usual care alone.
Article Synopsis
- The study aimed to evaluate heart rate variability (HRV) in patients with pulmonary hypertension (PH) and examine if sleep apnea worsens HRV effects.
- Researchers compared 41 PH patients to 41 healthy controls, discovering that PH patients had significantly lower HRV across different measures, including high frequency and low frequency metrics.
- The findings showed that sleep apnea did not further impact HRV in PH patients, suggesting that the impaired HRV seen in these individuals was not exacerbated by the presence of sleep apnea.
Overnight extracellular rostral fluid shifts have been shown to be of importance in patients with fluid-retaining states and are associated with a higher prevalence of sleep apnea. Pulmonary hypertension is frequently associated with right ventricular dysfunction and progressive right ventricular failure, and an increased prevalence of sleep apnea has been described. In light of the importance of fluid shifts in the pathophysiology of sleep apnea, we aimed to explore temporal fluid shifts in patients with pulmonary hypertension with and without sleep apnea.
View Article and Find Full Text PDFObjectives: To evaluate if treatment with continuous positive airway pressure (CPAP) compared to usual care in stroke patients with obstructive sleep apnea (OSA) over one month reduces delta and alpha oscillations on quantitative electroencephalography (EEG) in association with improvements in cognitive or functional outcomes.
Methods: Spectral EEG analysis was performed in patients with subacute stroke and OSA randomized to usual care or CPAP treatment from a previous study.
Results: A total of 23 subjects were included.