Clinical and molecular evaluation of insulin autoimmune syndrome in a woman with Graves' disease who subsequently became pregnant: A case report.

Insulin autoimmune syndrome or Hirata's disease is a rare condition characterized by hypoglycemia associated with endogenous autoimmune hyperinsulinism. This report concerns the case of a 28-year-old Latin American woman with Graves' disease who developed insulin autoimmune syndrome and then subsequently became pregnant. She displayed symptoms related to severe hypoglycemia due to hyperinsulinemia, elevated C-peptide, and anti-insulin antibodies.

Persistent oligonecrozoospermia after asymptomatic SARS-CoV-2 infection. A case report and literature review.

COVID-19 is known to have deleterious effects on different systems such as the respiratory, cardiovascular, central nervous, and gastrointestinal. However, conflicting data about the possible implications for male reproductive health and fertility have been reported. In addition, the long-term consequences of SARS-CoV-2 infection remain unclear.

[Clinical and evolutionary characteristics of incidental pituitary adenomas: retrospective multicenter study].

Introduction: Pituitary incidentalomas (PIs) are lesions found incidentally in the pituitary on imaging performed for reasons unrelated to pituitary disease.

Methods: A cross-sectional, retrospective and descriptive study was carried out with the aim of analyzing the clinical and evolutionary characteristics of a population of patients with PIs in the city of Córdoba.

Results: A total of 67 patients were included, 67% female, with a median age at diagnosis of 44 years.

[Cushing's disease in pregnancy and treatment with cabergoline: obstetric and neonatal results].

Introduction:: Cushing's disease (CD) is rare during pregnancy and is associated with significant maternal and fetal complications. The aim was to report the case of a patient with CD who achieved pregnancy and delivery without complications after treatment with low doses of cabergoline.

Methods:: A 29-year-old woman diagnosed with CD (ACTH-secreting macro-tumor that produces displacement of the optic chiasm, infiltrates the right cavernous sinus and includes the internal carotid artery).

Clitoromegaly due to an epidermal inclusion cyst: A case report.

Background: Clitoromegaly is often a sign of androgen excess; however, non-hormonal causes must be ruled out. We report the case of an adolescent with isolated clitoromegaly without clinical or biochemical evidence of hyperandrogenism.

Case: A 16-year-old female was referred due to a clitoromegaly of 12 months of evolution.

[Main endocrine disruptors related to female reproductive health: biological basis of their association].

Endocrine disruptors (EDs) are those chemical substances capable of interfering with hormonal homeostasis, altering the synthesis, function, storage and / or metabolism of hormones. These substances are found in the environment and in a wide variety of products for daily use, so human exposure is permanent. Animal experiments have confirmed the capacity of EDs to induce reproductive disorders, which is why it has been suggested that they could be an important factor in causing human subfertility.

[Surgical treatment in acromegaly: experience in Córdoba].

Introduction: Acromegaly prevalence is 35-70 / million. Transsphenoidal surgery is the first-line treatment, with a remission rate of 80% for microadenomas and 50% for macroadenomas. Our aim was to evaluate the surgical results in Córdoba and determine predictive remission factors due to the lack of records.

Favorable outcome of SARS-CoV-2 infection in a patient with pituitary insufficiency.

Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outbreak originated in Wuhan (China) rapidly turned into a pandemic. Due to a national compulsive decree of quarantine, office visits for chronic disease control were delay. Hypopituitarism includes all clinical conditions that result in partial or complete failure of the pituitary gland's ability to secrete hormones.

Pregnancy outcomes in women with polycystic ovary syndrome in two Latin American populations.

Pregnancy complications and obstetric outcomes were compared in 80 Chilean (PPCOS) and 70 Argentinian (PPCOS) pregnant women. Reference groups of Chilean and Argentinian normal pregnant women from the same antenatal care units were also compared. PPCOS showed a higher prevalence of gestational diabetes mellitus (GDM) (OR, 2.

[Polycystic ovary sindrome: impact on reproductive and maternal fetal health].

Unlabelled: Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism (H), oligo-anovulation (O) and / or polycystic ovaries (P). There is currently little information on perinatal complications.

Objective: to investigate obstetric and neonatal characteristics of women with PCOS in our population.

[Update on endocrinology: management of prolactinomas during pregnancy].

Unlabelled: The prolactinomas are the most common functioning pituitary tumors. The hyperprolactinemia is associated with anovulation and infertility.

Objectives: a) describe the relationship between hyperprolactinemia and fertility, b) review the results of the use of dopamine agonists during pregnancy and embryo-fetal development and c) review the therapeutic management in micro and macroprolactinomas during pregnancy.

Hyperandrogenism produced by ovarian tumors in women at different life stages.

Objective: to evaluate the different presentations of hyperandrogenism produced by ovarian tumors in women at different life stages

Design: case report.

Setting: academic institutions.

Patient(s): 3 patients at different life stages, with increased androgen levels.

Metabolic profile of the different phenotypes of polycystic ovary syndrome in two Latin American populations.

Objective: To evaluate the metabolic profile of Chilean and Argentinian women with polycystic ovary syndrome (PCOS) according to the Rotterdam criteria.

Design: Observational cross-sectional study.

Setting: Academic centers.

[Polycystic ovary syndrome: physiopathology review].

Polycystic ovary syndrome (PCOS), the most common gynecological endocrinopathy in women of reproductive age, is characterized by hyperandrogenism, chronic anovulation and /or polycystic ovaries. Although the cause of PCOS is still unknown, there are several hypotheses attempting to explain the primary defect; the most commonly accepted is insulin resistance. Due to its high prevalence, the patients have increased risk of developing metabolic and cardiovascular alterations.

Clinical, metabolic, and endocrine parameters in response to metformin and lifestyle intervention in women with polycystic ovary syndrome: a randomized, double-blind, and placebo control trial.

The aim of this study was to evaluate the effects of metformin in addition to diet and exercise on endocrine and metabolic disturbances in women with polycystic ovary syndrome (PCOS) in a prospective, double-blind, randomized, placebo (PBO) control trial. Thirty women with insulin resistance and PCOS received lifestyle modification and 1500 mg of metformin or placebo for 4 months. Before and after treatment, body mass index, waist/hip ratio, blood pressure, hirsutism, and menstrual patterns were evaluated.

Pregnancies associated with primary adrenal insufficiency.

Objective: To provide a framework for the clinical presentation, evolution, treatment, and outcome of the unusual association between primary adrenal insufficiency (AI) during pregnancy and life-threatening complications for the mother and fetus.

Design: Case reports.

Setting: Pregnant women with AI treated in the Endocrine and Diabetes Department, Hospital Universitario de Maternidad y Neonatología, Córdoba, Argentina.