Publications by authors named "Carolina Bortolozzo Graciolli Facanali"
Article Synopsis
- - The study investigates the relationship between Religiosity/Spirituality (R/S) and Quality of Life (QoL) among 151 Crohn's disease patients at a medical facility in Brazil, using various questionnaires to gather data.
- - Results indicated that the majority of participants had high levels of religious and spiritual engagement, but this did not correlate with improved QoL or differences in disease phenotypes.
- - The authors conclude that while R/S is prevalent among patients, it may serve more as a tool for treatment adherence rather than impacting quality of life directly, highlighting the need for diverse participant samples for future evaluations.
Background: Despite major advances in the clinical treatment of inflammatory bowel disease, some patients still present with acute colitis and require emergency surgery.
Aims: To evaluate the risk factors for early postoperative complications in patients undergoing surgery for acute colitis in the era of biologic therapy.
Methods: Patients with inflammatory bowel disease admitted for acute colitis who underwent total colectomy at a single tertiary hospital from 2012 to 2022 were evaluated.
Gastric and Duodenal Fistulas in Crohn's Disease, a Surgical Challenge: Report of 5 Cases and a Review of the Literature.
Am J Case Rep
September 2023
BACKGROUND Fistulas involving the stomach and duodenum in Crohn's disease are rare (occurring in less than 1% of patients). Here, we reviewed registers from 855 patients with Crohn's disease treated in our service from January 2007 to December 2020 and found 4 cases of duodenal fistula and 1 case of gastric fistula. CASE REPORT The fistula origin was in the ileocolic segment in all cases, and all of the patients underwent preoperative optimization with improvement of nutritional status and infection control.
View Article and Find Full Text PDFBACKGROUND Lipomas are benign, slow-growing mesenchymal neoplasms, more prevalent in females, with a peak incidence in the fifth to sixth decades of life. Generally, due to their low clinical relevance, they receive little attention in the literature. Uncommon in the colon, lipomas are most often identified as an incidentaloma in asymptomatic patients during colonoscopy, and overlapping with epithelial lesions is a rare finding.
View Article and Find Full Text PDFPerianal fistulizing Crohn's disease is associated with a higher prevalence of HPV in the anorectal fistula tract. A comparative study.
Clinics (Sao Paulo)
June 2023
Background & Aims: Perianal fistulizing Crohn's disease is the main risk factor for anal cancer in patients with inflammatory bowel disease. Whether this occurs due to a higher frequency of human papillomavirus remains unclear. The authors aimed to evaluate the prevalence of HPV and high-risk HPV in patients with perianal Crohn's disease, compared with a control group.
View Article and Find Full Text PDFArticle Synopsis
- Tuberculosis (TB) is a significant global health issue, particularly posing risks for ulcerative colitis (UC) patients receiving anti-TNF therapy, like adalimumab, which can increase susceptibility to infections like isolated neurotuberculosis (NTB).
- This article details a case of a 34-year-old woman with severe UC who developed isolated NTB after four years on adalimumab, presenting with persistent headaches, fever, and night sweats, despite prior negative TB screenings.
- The patient improved after stopping the immunosuppressive therapy and starting a multi-drug treatment regimen, highlighting the importance of early detection and intervention in TB cases to prevent serious complications.
Background: Behçet's disease is a rare immune-mediated disorder that can affect the gastrointestinal tract. The prevalence and extension of small bowel involvement is largely unknown.
Objective: The aim of this study was to describe the small bowel lesions diagnosed by double-balloon enteroscopy (DBE) and to verify if these findings were associated to the presence of gastrointestinal symptoms and disease activity after long-term follow-up.
BACKGROUND Central venous catheterization (CVC) is indispensable in the management of critically ill patients in the emergency room and intensive care units, either to avoid the various peripheral punctures and vasoactive drugs administration in decompensated patients, or even to administer parenteral nutrition. CVC is an invasive procedure with possible mechanical, infectious, and thrombotic complications. The complete knotting of a catheter is a rare complication.
View Article and Find Full Text PDFBackground: Takayasu's arteritis (TA) and inflammatory bowel disease (IBD) are chronic inflammatory granulomatous disorders that have rarely been concomitantly reported in case reports and small case series.
Objective: We report a series of seven cases of TA and IBD association in two referral centers with a comprehensive review of literature.
Methods: We analyzed retrospectively the electronic medical charts of TA-IBD patients at the University Hospital of São Paulo, Brazil, and at the Sheba Medical Center at Tel Aviv University, Israel.
Background: Analysis of the Twitter activity on #Crohn's, identifying individuals with interest in Crohn's disease on Twitter.
Methods: A historic cohort study was conducted about Twitter activity evaluation of #Crohn's analyzed over a period of 9 years. For the Twitter analysis, a health-care social media analytics tool, Symplur Signals, was adopted.