Chemotherapy as a risk factor for caries and gingivitis in children with acute lymphoblastic leukemia: A retrospective cohort study.

Background: Dental and oral anomalies are among the most common long-term side effects of childhood cancer therapy.

Aim: To evaluate chemotherapy as a risk factor for caries lesions and gingivitis in children with acute lymphoblastic leukemia (ALL) treated with the ALL IC-BFM 2009 chemotherapy protocol.

Design: A retrospective cohort study was designed.