Multifunctional Polypyrrole-Based Textile Sensors for Integration into Personal Protection Equipment.

Integrated safety sensors for personal protection equipment increasingly attract research activities as there is a high need for workers in delicate situations to be physically monitored in order to avoid accidents. In this work, we present a simple approach to generate thin, homogeneous polypyrrole (PPy) layers on flexible textile polyamide fabrics. PPy layers of 0.

Neocarzilin A Is a Potent Inhibitor of Cancer Cell Motility Targeting VAT-1 Controlled Pathways.

The natural product neocarzilin A () was discovered decades ago, and despite its potent cytotoxic effects no mode of action studies have been performed up to date. Synthesis of neocarzilins A, B, and C and a stereoisomer of provided insights into structural preferences as well as access to probes for functional studies.  turned out to be the most active member and was not only effective against cell proliferation but also migration, a novel and so far overlooked activity.