Investigation of mentalizing and visuospatial perspective taking for self and other in Asperger syndrome.

Mentalizing refers to making inferences about other people's mental states, whereas visuospatial perspective taking refers to inferring other people's viewpoints. Both abilities seem vital for social functioning; yet, their exact relationship is unclear. We directly compared mentalizing and visuospatial perspective taking in nineteen adults with Asperger syndrome (AS) and fifteen control participants with the same stimulus material.

Differential involvement of the posterior temporal cortex in mentalizing but not perspective taking.

Understanding and predicting other people's mental states and behavior are important prerequisites for social interactions. The capacity to attribute mental states such as desires, thoughts or intentions to oneself or others is referred to as mentalizing. The right posterior temporal cortex at the temporal-parietal junction has been associated with mentalizing but also with taking someone else's spatial perspective onto the world--possibly an important prerequisite for mentalizing.