Methylprednisolone alone or combined with cyclosporine or mycophenolate mofetil for the treatment of immune-mediated hemolytic anemia in dogs, a prospective study.

Background: Benefit of adding a second-line immunosuppressive drug to glucocorticoids for the treatment of non-associative immune-mediated hemolytic anemia (naIMHA) in dogs has not been defined prospectively.

Hypothesis/objectives: Evaluate the effectiveness of different immunosuppressive protocols in naIMHA dogs.

Animals: Forty-three client-owned dogs.