Publications by authors named "Carola Mietag"
Article Synopsis
- Recent estimates suggest that common genetic variations may play a significant role in hereditary breast cancer risk, particularly due to alleles with low penetrance but high prevalence.
- The tumor suppressor gene DMBT1 has been linked to breast cancer, with studies in mice identifying it as a potential factor influencing breast cancer risk.
- Two specific SNPs (DMBT1 c.-93C>T and DMBT1 c.124A>C) have been associated with increased breast cancer risk in women over 60, showing altered promoter activity that correlates with lower DMBT1 levels.
Background: Viral load quantification is established in the clinical management of chronic Hepatitis B virus (HBV) infection for assessing efficacies and resistance developments in anti-viral drug treatment.
Objectives: The fully automated COBAS AmpliPrep/COBAS TaqMan HBV Test, v2.0 was evaluated for the linear measuring range and the inclusivity of HBV genotype determination in EDTA plasma and serum samples.