Publications by authors named "Carol L Clarke"
Background: An adult male owl monkey (Aotus nancymae) underwent a splenectomy. When the spleen was removed, a small, nodular mass slightly bulging over the splenic surface was noted.
Methods: The mass was examined by light and transmission electron microscopy and by immunohistochemistry.
A rhesus macaque (Macaca mulatta) infected with simian-human immunodeficiency virus (SHIV) while undergoing AIDS research, required a comprehensive physical examination when it presented with slight peripheral edema, hypoalbuminemia, and proteinuria. Many of the clinical findings were consistent with nephrotic syndrome, which is an indication of glomerular disease, but the possibility of concurrent disease needed to be considered because lentiviral induced immune deficiency disease manifests multiple clinical syndromes. The animal was euthanized when its condition deteriorated despite supportive care that included colloidal fluid therapy.
View Article and Find Full Text PDFDetection and clearance of Syphacia obvelata infection in Swiss Webster and athymic nude mice.
Contemp Top Lab Anim Sci
May 2004
Article Synopsis
- The routine health-surveillance program utilizes Swiss Webster mice, tested for infections every 7 weeks, and includes athymic nude mice to detect pinworm infections.
- Research suggested that athymic nude mice, lacking a thymus, would be more susceptible to pinworm infections, making them better sentinels.
- However, results showed no significant difference in detection ability between the two mouse types, with Swiss Webster mice clearing infections effectively while athymic mice did not, indicating no advantage in using nude mice for detection.