Publications by authors named "Carol Fernandes"

Article Synopsis
  • A case study of a 41-year-old male with DD revealed that he developed hypothyroidism after starting acitretin, which is a rare side effect.
  • Despite initially benefiting from the treatment, acitretin was discontinued due to side effects, highlighting the need for regular blood monitoring during its use.
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  • A 41-year-old man with recent HIV diagnosis presented with severe symptoms including fever, skin lesions, and confusion, leading to septic shock and multiorgan dysfunction due to AIDS-related disseminated histoplasmosis.
  • Despite initial concerns, he received a timely diagnosis involving Histoplasma spp. and progressed to intensive care treatment that included antifungal therapy and necessary life support measures.
  • Ultimately, after 32 days in the ICU and a comprehensive management plan, he improved and was discharged on oral medications, underscoring the importance of recognizing histoplasmosis in advanced HIV patients.
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Article Synopsis
  • Recent clinical research highlights proenkephalin (PENK) as a potential biomarker for early detection of acute kidney injury (AKI) in liver transplantation patients.
  • In a study of 57 patients, PENK was notably elevated in those with severe AKI both preoperatively and 48 hours post-surgery, outperforming other biomarkers like cystatin-C and serum creatinine in terms of sensitivity and specificity.
  • Findings suggest that incorporating PENK alongside other kidney function tests could improve the management and prevention of progression in AKI post-liver transplantation.
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Here, we report a case of Acute promyelocytic leukemia (APL) with three way complex translocation involving chromosomes 4, 15, and 17. Although chromosome 4 is most commonly associated chromosome in three way translocation, present case is the first report with four novel co-existent findings of new break point region on chromosome 4, new cyclic mechanism with simultaneous breaks, presence of a co-existent tetrasomy 8 and FLT3 ITD positivity.; Comprehensive assessment highlight the utility of combining morphology, immunophenotyping, karyotyping, fluorescence in situ hybridization, and molecular studies for better characterization, optimal management of APL with a better understanding of the pathogenic mechanism and prognosis of the disease.

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Background: Topical antifungal agents along with the steroids may provide not only rapid symptomatic relief but also clearance of disease causing fungi in inflamed cutaneous mycoses (ICM).

Aim: To assess the efficacy and safety of fixed dose combination (FDC) of Eberconazole nitrate 1% and Mometasone furoate 0.1% w/w cream, in subjects with ICM.

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Actinomycosis is a chronic, progressive, suppurative infection, prevalent over the neck, thorax or abdomen. As it rarely occurs with few clinical symptoms, its diagnosis requires a high index of clinical suspicion. We report a case of primary cutaneous actinomycosis affecting the back.

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A case of non hereditary connective tissue naevus without any association with systemic complaints, in a 20-year old male is reported.

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