Management of elderly patients with glioblastoma: current status with a focus on the post-operative radiation therapy.

Glioblastoma (GBM) is one of the most malignant primary intracranial neoplasms. This review aims to summarize the treatment of elderly patients with newly diagnosed GBM, with a focus on the radiation therapy (RT) approach. The available literature was reviewed, and we describe the most significant results relating to the post-operative approach of elderly GBM patients.

The effect of water immersion and acute hypercapnia on ventilatory sensitivity and cerebrovascular reactivity.

The partial pressure of end tidal carbon dioxide (PETCO ), ventilatory sensitivity to CO , and cerebral perfusion are augmented during thermoneutral head out water immersion (HOWI). We tested the hypotheses that HOWI and acute hypercapnia augments minute ventilation, ventilatory sensitivity to CO , cerebral perfusion, and cerebrovascular reactivity to CO . Twelve subjects (age: 24 ± 3 years, BMI: 25.