Factors influencing fatigue in UK nurses working in respiratory clinical areas during the second wave of the Covid-19 pandemic: An online survey.

Aims And Objectives: This study explores UK nurses' experiences of working in a respiratory clinical area during the COVID-19 pandemic over winter 2020.

Background: During the first wave of the pandemic, nurses working in respiratory clinical areas experienced significant levels of anxiety and depression. As the pandemic has progressed, levels of fatigue in nurses have not been assessed.

Experimental evidence for recovery of mercury-contaminated fish populations.

Anthropogenic releases of mercury (Hg) are a human health issue because the potent toxicant methylmercury (MeHg), formed primarily by microbial methylation of inorganic Hg in aquatic ecosystems, bioaccumulates to high concentrations in fish consumed by humans. Predicting the efficacy of Hg pollution controls on fish MeHg concentrations is complex because many factors influence the production and bioaccumulation of MeHg. Here we conducted a 15-year whole-ecosystem, single-factor experiment to determine the magnitude and timing of reductions in fish MeHg concentrations following reductions in Hg additions to a boreal lake and its watershed.

Experiences of nurses caring for respiratory patients during the first wave of the COVID-19 pandemic: an online survey study.

Background: Nurses have been at the forefront of the pandemic response, involved in extensive coordination of services, screening, vaccination and front-line work in respiratory, emergency and intensive care environments. The nature of this work is often intense and stress-provoking with an inevitable psychological impact on nurses and all healthcare workers. This study focused on nurses working in respiratory areas with the aim of identifying and characterising the self-reported issues that exacerbated or alleviated their concerns during the first wave of the COVID-19 pandemic.

'It's not one size fits all': a qualitative study of patients' and healthcare professionals' views of self-management for bronchiectasis.

Background: Bronchiectasis is a chronic respiratory condition that impacts significantly on individuals and healthcare services. Self-management is recommended in clinical guidelines for bronchiectasis as an intervention to enable patients to manage their condition, yet there is little evidence to support it.

Methods: Three face to face focus groups (17 adults with bronchiectasis) were conducted at three National Health Service (NHS) sites in North West England.

Oxygen alert wristbands (OxyBand) and controlled oxygen: a pilot study.

Despite the introduction of Oxygen Alert Cards, guidelines and audits, oxygen therapy remains overused in NHS practice, and this may lead to iatrogenic mortality. This pilot study aimed to examine the use of Oxygen Alert Wristbands (OxyBand) designed to alert health professionals who are delivering oxygen to patients to ensure that the oxygen is administered and titrated safely to the appropriate target saturations. Patients at risk of hypercapnic acidosis were asked to wear OxyBands while presenting to paramedics and health professionals in hospitals.

Transport of mercury on the finest particles results in high sediment concentrations in the absence of significant ongoing sources.

The mercury contaminated upper Penobscot Estuary in Maine provided a unique opportunity to rigorously examine the effect of sediment type and particle size on mercury concentrations in sediments, and to explain why sediments at different locations in the estuary had different mercury concentrations. This is because the Penobscot Estuary contains a large, well-mixed pool of mobile sediments of many different types (muds, sand, gravel, wood chips), which are the source of material for the permanently deposited surface sediments. Despite this mixing, average surface sediment mercury concentrations were very different in different locations, ranging from 238 ng/gdw to 1032 ng/gdw in the 11 subareas studied.

Research priorities for respiratory nursing: a UK-wide Delphi study.

Respiratory nurses make a significant contribution to the delivery of respiratory healthcare, but there is a dearth of nurse-led, practice-focused, published research. Using a modified three-round Delphi, this study sought to identify research priorities for respiratory nursing to inform a national research strategy. Study information and the survey link were sent electronically to members of UK professional respiratory organisations.

An evaluation of National Health Service England's Care Maker Programme: A mixed-methods analysis.

Aims And Objectives: To investigate the impact and sustainability of the Care Maker programme across England from the perspective of those involved in its delivery.

Background: The Care Maker programme was launched in England in 2013. It aims to support the "Compassion in Practice" strategy, with particular emphasis on the 6Cs of care, compassion, competence, communication, courage and commitment.

A wolf in sheep's clothing? Patients' and healthcare professionals' perceptions of oxygen therapy: An interpretative phenomenological analysis.

Background: Despite emerging evidence and guidelines, poor prescribing and administration of oxygen therapy persists. This study aimed to explore healthcare professionals' (HCPs) and patients' perceptions of oxygen.

Design: Semi-structured interviews with 28 patients and 34 HCPs.

Difficult decisions: An interpretative phenomenological analysis study of healthcare professionals' perceptions of oxygen therapy in palliative care.

Background: The role of oxygen therapy to palliate dyspnoea is controversial. Without a clear evidence base oxygen is commonly prescribed, sometimes to the detriment of patients. This use of oxygen appears to be an entrenched culture, the roots of which remain obscure.

How do health-care professionals perceive oxygen therapy? A critical interpretive synthesis of the literature.

Oxygen is one of the commonest health-care interventions worldwide. This might suggest that health-care professionals (HCPs) would be knowledgeable and familiar with its uses and limitations. Yet it is apparent, through clinical audit, that oxygen is probably misunderstood by many HCPs.

How do respiratory patients perceive oxygen therapy? A critical interpretative synthesis of the literature.

Oxygen therapy is a common intervention in health care worldwide; yet, despite universal use, it is evident through poor practice that oxygen is often prescribed and administered injudiciously. It is proposed that possibly an influencing culture presides, whereby oxygen is often poorly understood and uncertainty regarding its use exists. It is unclear where the origins of this culture lie but exploring perceptions may enlighten the problem.

Investigation of uptake and retention of atmospheric Hg(II) by boreal forest plants using stable Hg isotopes.

Although there is now a general consensus among mercury (Hg) biogeochemists that increased atmospheric inputs of inorganic Hg(II) to lakes and watersheds can result in increased methylmercury (MeHg) concentrations in fish, researchers still lack kinetic data describing the movement of Hg from the atmosphere, through watershed and lake ecosystems, and into fish. The use of isotopically enriched Hg species in environmental studies now allows experimentally applied new Hg to be distinguished from ambient Hg naturally present in the system. Four different enriched stable Hg(II) isotope "spikes" were applied sequentially over four years to the ground vegetation of a microcatchment at the Experimental Lakes Area (ELA) in the remote boreal forest of Canada to examine retention of Hg(II) following deposition.

Long-term wet and dry deposition of total and methyl mercury in the remote boreal ecoregion of Canada.

Although a positive relationship between atmospheric loadings of inorganic mercury (Hg(II)) to watersheds and concentrations of methyl mercury (MeHg) in fish has now been established, net wet and dry deposition of Hg(II) and MeHg to watersheds remains challenging to quantify. In this study, concentrations and loadings of total mercury (THg; all forms of Hg in a sample) and MeHg in open area wet deposition, throughfall, and litterfall were quantified atthe remote Experimental Lakes Area in the boreal ecoregion, NW Ontario, Canada. Between 1992 and 2006, mean annual THg and MeHg loadings in the open were 36 +/- 17 and 0.

Effect of pH on intracellular accumulation of trace concentrations of Hg(II) in Escherichia coli under anaerobic conditions, as measured using a mer-lux bioreporter.

The effects of pH on the uptake and accumulation of Hg(II) by Escherichia coli were determined at trace, environmentally relevant, concentrations of Hg and under anaerobic conditions. Hg(II) accumulation was measured using inducible light production from E. coli HMS174 harboring a mer-lux bioreporter plasmid (pRB28).

Evaluation of mercury toxicity as a predictor of mercury bioavailability.

Many studies on bioavailability of toxic metals have made the assumption that observation of toxicity is evidence thatthe metal was taken into the cells (i.e., was "bioavailable").

The rise and fall of mercury methylation in an experimental reservoir.

For the past 9 years, we experimentally flooded a wetland complex (peatland surrounding an open water pond) at the Experimental Lakes Area (ELA), northwestern Ontario, Canada, to examine the biogeochemical cycling of methyl mercury (MeHg) in reservoirs. Using input-output budgets, we found that prior to flooding, the wetland complex was a net source of approximately 1.7 mg MeHg ha(-1) yr(-1) to downstream ecosystems.

Reactivity and mobility of new and old mercury deposition in a boreal forest ecosystem during the first year of the METAALICUS study. Mercury Experiment To Assess Atmospheric Loading In Canada and the US.

The METAALICUS (Mercury Experiment To Assess Atmospheric Loading In Canada and the US) project is a whole ecosystem experiment designed to study the activity, mobility, and availability of atmospherically deposited mercury. To investigate the dynamics of mercury newly deposited onto a terrestrial ecosystem, an enriched stable isotope of mercury (202Hg) was sprayed onto a Boreal forest subcatchment in an experiment that allowed us, for the first time, to monitor the fate of 'new' mercury in deposition and to distinguish it from native mercury historically stored in the ecosystem. Newly deposited mercury was more reactive than the native mercury with respect to volatilization and methylation pathways.

Demographic consequences of inflorescence-feeding insects for Liatris cylindracea, an iteroparous perennial.

While floral herbivores and predispersal seed predators often reduce plant reproductive output, their role in limiting plant fitness and population growth is less clear, especially for iteroparous perennial plant species. In this study we experimentally excluded floral herbivores and predispersal seed predators (insecticide spray versus water control) over a 2-year period to examine the effect of inflorescence-feeding insects on levels of seed production, seedling emergence, and juvenile establishment for Liatris cylindracea, an iteroparous perennial plant. In addition, we collected detailed demographic data on all life stage transitions for an additional set of individuals in the same population over 4 years.

QUANTITATIVE GENETICS OF SIZE AND PHENOLOGY OF LIFE-HISTORY TRAITS IN CHAMAECRISTA FASCICULATA.

Despite numerous adaptive scenarios concerning the evolution of plant life-history phenologies few studies have examined the heritable basis for and genetic correlations among these phenologies. Documentation of genetic variation for and covariation among reproductive phenologies is important because it is this variation/covariation that will determine the potential for response to evolutionary forces. To address this problem, I conducted a breeding experiment to determine narrow-sense heritabilities for and genetic correlations among the phenologies of life-history events and plant size in Chamaecristafasciculata, a temperate summer annual plant species.

SPATIAL AND TEMPORAL VARIATION IN SELECTION ON CORRELATED LIFE-HISTORY TRAITS AND PLANT SIZE IN CHAMAECRISTA FASCICULATA.

Intraspecific studies of selection on multiple traits of a plant's life history provide insight as to how the composite life history of an organism evolves. Current understanding of selection on plant life-history traits is deficient in three important areas: 1) the effects of selection through correlated traits, 2) the effects of selection on a trait throughout the plant's lifetime, and 3) spatial and temporal variation in selection on plant life-history traits among populations and years. This study documents spatial and temporal variation in selection on three life-history and two morphological traits for two natural populations of Chamaecrista fasciculata, a native summer annual.

REPRODUCTIVE PHENOLOGIES IN LOBELIA INFLATA (LOBELIACEAE) AND THEIR ENVIRONMENTAL CONTROL.

Flowering and fruiting phenologies of individual plants and flowers of Lobelia inflata, a North American summer annual, were studied in the field and greenhouse to determine whether onset of flowering and fruit maturation were correlated, and the degree to which these reproductive phenologies were influenced by the environment. Within each of two field populations, larger plants flowered earlier and produced more flowers than smaller plants. Onset of flowering was positively correlated with onset of fruit maturation but not perfectly so.

Extrafloral nectaries: ants, herbivores and fecundity in Cassia fasciculata.

Extrafloral nectaries of Cassia fasciculata attract nectar feeding ants which protect the plant against leaf herbivores. High ant visitation in late July coincided with high herbivore densities at two sites in east central Iowa. The highest level of leaf herbivory occurred during the time of flowering and early fruit filling, just after the peak of herbivore and ant activity.