Factors related to amphotericin-B-induced rigors (shivering).

Amphotericin-B is the only parenteral agent currently available to treat systemic fungal infections. Pyrogenesis, accompanied by severe shivering, is a distressing side effect. Possible risk factors of developing this reaction have not been reported.

Impact of an educational program on physician cancer control knowledge and activities.

Continuing medical education (CME) programs are a common way for physicians to keep up with new developments in medical care. CME has been criticized as poorly evaluated at best and ineffective at worst. Proposed modifications in the traditional CME format include a role for influential peers, physician discussion groups, and self-formulated contracts.

The relationship between axillary and core body temperature measurements.

The goal of this study was to assess the accuracy of the axillary site as an indicator of core body temperature. Data from 30 core body temperatures, 30 electronic axillary temperatures, and 30 mercury-in-glass axillary temperatures in nonpostoperative intensive care unit patients are reported. Core and axillary temperatures were simultaneously measured in each patient.

Intraperitoneal alpha interferon for ovarian cancer: a case report.

Though therapeutic advances have been made in the treatment of ovarian carcinoma, success at achieving a cure in women with advanced disease has been elusive. Since advanced ovarian carcinoma is frequently confined to the peritoneum, the use of intraperitoneal (IP) chemotherapy is being studied. Dose-limiting toxicity and extended nausea and vomiting associated with intraperitoneal chemotherapy are problems with several of the drugs under study.