Acute cerebellar hemorrhage with brainstem compression in contrast with benign cerebellar hemorrhage.

Twenty six cases of cerebellar hemorrhages were reviewed and analyzed. Two patients were comatose on admission and showed clinical evidence of brainstem compression; they were successfully revived after evacuation of the hematomas. This was in contrast with six other comatose patients who did not have evacuation and subsequently died within 48 hours.

Studies on cell migration and axon guidance in the developing distal auditory system of the mouse.

The events that take place along the potential route of distal auditory axons (future vestibular component) prior to and during their outgrowth were examined morphologically using timed mouse embryos. During embryonic (E) day 9.5 a discrete zone of cell death appears in the rostrolateral wall of the otic cup.

Intracranial tuberculoma: conservative management.

Twenty cases of intracranial tuberculoma were treated by us. A clinical-radiographic syndrome was recognized, consisting of an avascular enhancing mass lesion surrounded by marked edema and associated with relatively less severe clinical manifestations than would have been expected from the size and location of the lesion. This allowed successful medical therapy with three antituberculous drugs for an average of 12 months.

Monoamine-related markers of depression: changes following treatment.

Changes in adrenoceptor and serotonin receptor activities, and platelet serotonin uptake, in a group of moderately depressed patients before and during treatment have been monitored. alpha 2 and beta-adrenoceptor densities on platelets and lymphocytes were markedly higher before treatment commenced and decreased to approximately control values following clinical response to drug treatment; patients not responding to such treatment failed to show any attenuation of the receptor hypersensitivity. Responders and non-responders showed differing receptor affinity for the ligands at the conclusion of the treatment period.

Immunofluorescence of green monkey kidney cells infected with adenovirus 12 and with adenovirus 12 plus simian virus 40.

Malmgren, Richard A. (National Cancer Institute; Bethesda, Md.), Alan S.