Publications by authors named "Carmine E Pascale"

Article Synopsis
  • Cardiac resynchronization therapy (CRT) is commonly used for heart failure patients, but its compatibility with cardiac magnetic resonance (CMR) imaging is uncertain.
  • This study aimed to evaluate the safety of a "CRT off-on" protocol during CMR and to observe its immediate effects on left ventricular (LV) function.
  • Results showed that while the protocol was generally safe, only a few patients had analyzable data, and while there were improvements in LV function, technical issues highlight the need for better methods during CRT imaging.
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We describe the case of a young man with an initial diagnosis of acute myocarditis that was finally recognized as a familial left-dominant arrhythmogenic cardiomyopathy. The diagnostic process was also based on demonstration, serial cardiac magnetic resonance imaging, and typical patterns of myocardial damage, including features of the disease's inflammatory "hot phase".

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Background: Mitral valve prolapse (MVP) is characterized by an abnormal movement of the valvular apparatus which may affect the papillary muscles (PMs) function and structure. Aim of the study was to investigate abnormal PM signal in MVP by using cardiac magnetic resonance imaging (MRI).

Methods And Results: We enrolled 47 consecutive patients with MVP evaluated by cardiac MRI.

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Alterations in myocardial energy metabolism as demonstrated by magnetic resonance spectroscopy (MRS) are critically involved in heart failure development. H-MRS allows investigation of the role of myocardial lipid accumulation in the pathophysiology of heart failure. With P-MRS, the most useful parameter is the cardiac adenosine triphosphate to phosphocreatine ratio, which is typically reduced in the failing heart and correlates with cardiac functional status.

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