Publications by authors named "Carmine Di Stasi"

Background And Objectives: The optimal mechanical thrombectomy technique for distal, medium vessel occlusion (DMVO) stroke remains unknown. We aimed to compare the safety and efficacy of 2 thrombectomy first-line approaches, direct aspiration (DA), and combined technique (CT) in patients with DMVOs.

Methods: We conducted a retrospective review of a prospectively collected multicenter database of patients with DMVOs (at or distal to M2 and A1), who underwent mechanical thrombectomy with JET D reperfusion catheters between January 2020 and December 2021.

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Background And Objectives: This multicenter study aimed to assess the safety and efficacy of the Woven EndoBridge (WEB) device for treating unruptured wide-neck intracranial bifurcation aneurysms (WIBAs) with short-, mid-, and long-term follow-ups (FUPs).

Methods: Consecutive patients with unruptured WIBAs treated with WEB between December 2014 and January 2018 were included. Patient, aneurysm, and device characteristics were collected and analyzed retrospectively.

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Article Synopsis
  • The study aimed to compare the effectiveness and safety of two types of vascular closure devices (VCDs): balloon-based and non-balloon-based.
  • Conducted between March 2021 and May 2022, it involved 2,373 participants and focused on 1,672 patients, evaluating successful hemostasis, failure management, and safety rates of complications.
  • Results indicated that non-balloon VCDs had a higher rate of successful hemostasis (96.5%) compared to balloon VCDs (85.9%), although non-balloon devices had a higher incidence of arteriovenous fistulas (1.57% vs. 0%).
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PURPOSE Renal artery aneurysms (RAAs) are rare in the general population, although the true incidence and natural history remain elusive. Conventional endovascular therapies such as coil embolization or covered stent graft may cause sidebranches occlusion, leading to organ infarction. Flow-diverters (FD) have been firstly designed to treat cerebrovascular aneurysms, but their use may be useful to treat complex RAAs presenting sidebraches arising from aneurysmal sac.

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Article Synopsis
  • * Out of 74 patients with RSH, 61 were found to have active bleeding, with successful conservative management in 19 cases, while 42 required glue embolization, which effectively improved hemoglobin levels.
  • * The glue embolization technique demonstrated safety, with no major complications, and showed that it could effectively stop bleeding by occluding the source without needing direct access to the bleeding point.
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Purpose: The aim was to compare a protocol of uterine artery embolization (UAE) consisting in three digital subtraction angiographies (DSAs)-Group A, with a protocol based on a single DSA-Group B.

Materials And Methods: This is a single-center prospective randomized study enrolling 20 women (mean age 41 years, range 22-55 years) with uterine fibroids treated with UAE, from January 2015 to February 2016. All UAEs were performed by two interventional radiologists using the same angiography machine.

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Objective: The objective is to report a single centre experience in the embolization of visceral artery pseudoaneurysms with N-butyl-cyanoacrylate-methacryloxy sulfolane (NBCA-MS).

Methods: A retrospective observational cohort study was conducted on data about all consecutive patients treated for visceral artery pseudoaneurysms in the Interventional Radiology Unit of SS Annunziata Hospital, in Taranto (Italy) between January 2016 and July 2020. Only patients treated with NBCA-MS embolization were included.

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Uterine fibroids embolization is a safe and effective organ sparing treatment for fibroid-related symptoms based on a broad range of published evidence including randomized-controlled trials. Indication to treatment is usually the presence of symptomatic uterine fibroids. In this review, a systematic search of journal articles relevant to the treatment of symptomatic uterine fibroids was conducted, with a special focus on the indication to treatment, technique, procedural outcomes and pain control.

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Article Synopsis
  • The study aimed to compare the effectiveness of three large-bore aspiration catheters for treating ischemic strokes caused by occlusions in the middle cerebral artery.
  • Conducted in three high-volume stroke centers in Italy, the research included 321 patients who underwent mechanical thrombectomy within 24 hours of stroke symptoms.
  • While there were no overall differences in recanalization rates among the three catheters, the Sofia 6 Plus catheter performed better in achieving successful first-pass recanalization, while rt-PA was linked to poorer outcomes in this regard.
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Background: Peripheral artery disease (PAD) represents one of the most relevant vascular complications of type 2 diabetes mellitus (T2DM). Moreover, T2DM patients suffering from PAD have an increased risk of major adverse cardiovascular events (MACE) and major adverse limb events (MALE). Sortilin, a protein involved in apolipoproteins trafficking, is associated with lower limb PAD in T2DM patients.

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Objective: Evaluate the efficacy and safety of renal artery embolization (RAE) for iatrogenic renal vascular injuries (IRVI) management at Fondazione Policlinico Universitario "A. Gemelli" IRCCS, in the last 5 years.

Methods: Retrospective analysis of all RAE procedures performed from January 2013 to December 2017.

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Pulmonary arteriovenous malformations (PAVMs) or fistulas are rare direct pathological connections between pulmonary arterial and venous circulation. Most of PAVMs are congenital and closely associated with hereditary hemorrhagic telangiectasia, but acquired PAVMs have also been described in the literature. Diagnosis of PAVMs is a priority for clinicians, in order to prevent potentially fatal events such as cerebrovascular stroke, systemic septic embolization, hemoptysis and hemothorax.

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Background: In liver cirrhosis, the renin-angiotensin-aldosterone system is involved in the pathogenesis of portal hypertension. Its effector, angiotensin II, is generated by angiotensin-converting enzyme (ACE). Serum ACE levels are affected by I/D polymorphism of its gene, with alleles I and D being associated, respectively, with lesser and greater activity of the enzyme.

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Objective: To evaluate effectiveness and safety of UFE as alternative to surgery, in treatment of uterine fibromatosis.

Methods/materials: 255 patients (aged 26-55) with symptomatic UF, indication for surgery, followed in our center (2000-2014), single or multiple fibroids, pain and/or functional/compressive disorders, underwent embolization: injection of PVA particles (150-900 μm) from distal portion of uterine arteries (ascending section). Primary end-point: flow-stop distally to injection site, disappearance of lesion design, preservation of flow in main trunk of UA.

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Background: Multidetector computed tomography angiography (MDCTA) and magnetic resonance angiography (MRA) are accurate techniques for selecting patients with peripheral arterial disease for surgical and endovascular treatment. No studies in the literature have directly compared MDCTA and MRA to establish which one should be employed, in patients suitable for both techniques, before endovascular treatment.

Purpose: To compare diagnostic performance of MDCTA vs MRA before endovascular intervention.

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Aim: To assess the prognostic role of baseline clinical, biochemical and radiological characteristics of patients with hepatocellular carcinoma (HCC) treated with the first transarterial chemoembolization (TACE) procedure.

Methods: Patients with HCC treated with conventional TACE in a tertiary care setting from 1997 to 2008 were retrospectively reviewed. Predictors of survival were identified using the Cox proportional regression model.

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We discuss a case of transvenous lead extraction (TLE) in a patient with a large vegetation. To prevent embolization, a Dormia basket was placed in the pulmonary artery trunk. After uncomplicated TLE, the basket was withdrawn, and vegetation material was retrieved from it.

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Objective: To assess the accuracy of a semiautomated 3-dimensional (3D) computed tomographic angiography software in the evaluation of lower limb stenoses compared to reader evaluation, using digital subtraction angiography (DSA) as standard of reference.

Materials And Methods: Forty patients with peripheral vascular occlusive disease underwent both DSA and computed tomographic angiography. The vascular tree was divided into 6 segments from distal aorta to popliteal artery.

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Background: Postpartum hematomas are a potentially serious obstetric complication for which management options are not standardized. We report successful treatment of a large postpartum hematoma using arterial embolization as primary approach.

Case: A 29-year-old woman at term gestation underwent vacuum-assisted vaginal delivery.

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Objective: To estimate the incidence of clinical failure after uterine leiomyoma embolization and identify possible risk factors.

Methods: One hundred seventy-six consecutive women undergoing uterine leiomyoma embolization were followed prospectively for a median of 48 months (range 12-84 months) to estimate the occurrence of clinical failure, defined as persistence or recurrence of leiomyoma symptoms, and any subsequent invasive treatment. Cumulative failure and reintervention rates were estimated by survival analysis and log-rank tests according to baseline patient characteristics.

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Purpose: To investigate the ionizing radiation dose, image quality, and diagnostic performance of computed tomographic (CT) angiography of the peripheral arteries with three different CT angiographic acquisition protocols, with use of pretreatment digital subtraction angiography (DSA) as the reference standard.

Materials And Methods: The study was approved by the institutional review board and performed in agreement with the 1990 Declaration of Helsinki and subsequent amendments. Each patient provided informed consent before undergoing CT.

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