Resistome and comparative genomics of clinical isolates of diarrheagenic Escherichia coli from Lima, Peru.

In order to describe the genomic characteristics related to antimicrobial resistance and comparative genomics of diarrheagenic Escherichia coli (DEC), 14 DEC isolates from the strain collection of the Instituto Nacional de Salud (INS) were subjected to genome sequencing. We used bioinformatic procedures to analyze the obtained sequences in order to look for microbial resistance genes and genetic regions related to pathotypes and phylogroups. Several antimicrobial resistance determinants were detected, but the production of beta-lactamases and mutations associated to quinolone resistance were the most relevant.

[Multidrug resistance of Salmonella infantis in Peru: a study through next generation sequencing].

Objectives.: To describe the phenotypic and genotypic patterns of the antimicrobial resistance of Salmonella Infantis in Peru.

Materials And Methods.