Publications by authors named "Carmen Socoteanu"
Background: In a recent cohort study, prolongation of the corrected QT interval (QTc) was associated with an independent increased risk of sudden cardiac death (SCD). We evaluated determinants of prolonged QTc and the relationship of prolonged QTc to SCD risk among patients with coronary artery disease in the general population.
Methods And Results: A case-control design was used.
Article Synopsis
- The study investigated the link between therapeutic methadone use and sudden cardiac death in a community over four years.
- Researchers compared cases of sudden cardiac death in patients with therapeutic methadone levels to those without, excluding individuals with drug use or overdoses.
- Results indicated a lower incidence of cardiac abnormalities in patients using methadone, suggesting a possible association between methadone and increased risk of sudden death, warranting further safety measures and research.
Article Synopsis
- The study examines the role of left ventricular (LV) dysfunction in sudden cardiac death (SCD) and identifies unique traits of SCD cases without LV dysfunction.
- Among 714 SCD cases, only 17% had their LV function assessed, revealing that 30% had severe LV dysfunction, while 48% had normal LV function.
- Those with normal LV function tended to be younger, had a higher percentage of females, were more likely to have seizure disorders, and had less established coronary artery disease, highlighting the need for better screening methods to identify at-risk individuals.