Publications by authors named "Carmen Schmid-Herrmann"
Hypophosphatasia (HPP) is an inherited, systemic disorder, caused by loss-of-function variants of the ALPL gene encoding the enzyme tissue non-specific alkaline phosphatase (TNSALP). HPP is characterized by low serum TNSALP concentrations associated with defective bone mineralization and increased fracture risk. Dental manifestations have been reported as the exclusive feature (odontohypophosphatasia) and in combination with skeletal complications.
View Article and Find Full Text PDFObjectives: Carriere Motion 3D™ appliance (CMA) represents a method for molar distalization and correction of class II malocclusion. The aim was to investigate the 3D effects of the CMA by superimposing digital models and cephalometric X-rays.
Materials And Methods: We retrospectively examined 16 patients treated with CMA in combination with class II elastics.
Mucopolysaccharidosis VI (MPS VI) is a hereditary lysosomal storage disease caused by the absence of the enzyme arylsulfatase B (ARSB). Craniofacial defects are common in MPS VI patients and manifest as abnormalities of the facial bones, teeth, and temporomandibular joints. Although enzyme replacement therapy (ERT) is the treatment of choice for MPS VI, the effects on the craniofacial and dental structures are still poorly understood.
View Article and Find Full Text PDFBackground: Mucopolysaccharidoses (MPS) are a group of rare metabolic diseases characterized by a wide spectrum of symptoms including progressive condylar resorption.
Aim: The aim of this study was to quantify the severity of condylar involvement in MPS I individuals in comparison with a group of non-MPS individuals and to describe how condylar changes may vary among the different types of MPS.
Design: Fifty panoramic radiographs of MPS patients (13.