Publications by authors named "Carmen Santagata"
Background: The benefits and timing of percutaneous dilatational tracheostomy (PDT) in Intensive Care Unit (ICU) COVID-19 patients are still controversial. PDT is considered a high-risk procedure for the transmission of SARS-CoV-2 to healthcare workers (HCWs). The present study analyzed the optimal timing of PDT, the clinical outcomes of patients undergoing PDT, and the safety of HCWs performing PDT.
View Article and Find Full Text PDFRisk and predictive factors of prolonged viral RNA shedding in upper respiratory specimens in a large cohort of COVID-19 patients admitted to an Italian reference hospital.
Annalisa Mondi Patrizia Lorenzini Concetta Castilletti Roberta Gagliardini Eleonora Lalle Carmen Santagata
Int J Infect Dis
April 2021
Article Synopsis
- The study analyzed COVID-19 patients in a hospital in Italy to explore factors influencing prolonged SARS-CoV-2 RNA shedding and viral clearance.
- It found that patients with comorbidities, lymphopenia, or moderate/severe respiratory issues had lower chances of viral clearance, with a median viral shedding duration of 18 days.
- Achieving viral clearance significantly improved clinical recovery rates and reduced the risk of death or the need for mechanical ventilation, emphasizing the necessity for timely hospital admission for symptomatic patients.
Article Synopsis
- Notarchirico in Southern Italy reveals the earliest evidence of Acheulean settlements with new archaeological findings, including bifaces, extending its history in Italy.
- Recent dating places these ancient occupations between 695 and 670 ka during the MIS 17 period, aligning with similar sites in France.
- The findings suggest rapid cultural expansion among adaptable hominins in Western Europe during fluctuating climate conditions, challenging the idea of refuge areas during glacial stages and highlighting the need to explore migration routes like the Sicilian pathway.
Article Synopsis
- The debate around bifacial shaping in Western Europe focuses on its origins and the defining characteristics of the Acheulean culture, highlighting the importance of Large Cutting Tools (LCTs) and technological advancements.
- Recent archaeological findings from the site of Notarchirico in Southern Italy provide a revised timeline, dating key excavated layers between 610 and 670 ka, suggesting widespread biface production during this period.
- A technological analysis of 32 tools from various archaeological layers demonstrates that early hominins effectively managed bifacial volume, revealing no noticeable differences in shaping and forms across levels, although the oldest layer showed high diversity despite lacking flint.