Publications by authors named "Carmen Mihai"
Systemic sclerosis (SSc) is a chronic autoimmune disorder with unknown triggering factors, and complex pathophysiologic links which lead to fibrosis of skin and internal organs, including the heart, lungs, and gut. However, more than 100 years after the first description of cardiac disease in SSc, sclerodermic cardiomyopathy (SScCmp) is an underrecognized, occult disease with important adverse long-term prognosis. Laboratory tests, electrocardiography (ECG) and cardiovascular multimodality imaging techniques (transthoracic 2D and 3D echocardiography, cardiac magnetic resonance (CMR), and novel imaging techniques, including myocardial deformation analysis) provide new insights into the cardiac abnormalities in patients with SSc.
View Article and Find Full Text PDFObjective. This study compared the eradication rates of of Helicobacter pylori (HP) infection by a 7-day and 14-day anti-HP regimen. Materials and Methods.
View Article and Find Full Text PDFSystemic sclerosis (SSc) is a chronic disease of unknown etiology. The main feature of SSc is microvascular disease, but contemporary studies in the field have confirmed the presence of macrovascular affectation. Due to its inflammatory background, and higher cardio- and cerebrovascular death rates, it is presumed that SSc is more frequently associated to accelerated atherosclerosis, similarly to other autoimmune diseases, such as systemic lupus erythematosus or rheumatoid arthritis.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate the prognostic significance of systolic pulmonary artery pressure (sPAP) measured through echocardiography in a large European cohort of scleroderma patients.
- A total of 1476 patients were analyzed, with findings showing that higher sPAP levels were linked to an increased risk of death, particularly for sPAP values above 36 mmHg, indicating its importance as an independent risk factor for mortality.
- The results suggest that an estimated sPAP greater than 36 mmHg at the initial examination correlates with poorer survival outcomes, regardless of pulmonary hypertension diagnosis confirmed through more invasive methods.
Background: Rheumatoid arthritis (RA) is associated with loss of overall functionality of the locomotion system and it is connected with substantial economic losses.
Objective: To describe the clinical characteristics and healthcare resource utilization characteristics and to analyze the correlations in a cross-sectional sample of 206 patients in Romania.
Method: RA cases have been enrolled from southern and western part of the country, covering a surface of 23 counties.