Publications by authors named "Carmen Marin Hinojosa"
Article Synopsis
- Detecting hidden cancers in patients with unexplained venous thromboembolism (VTE) is challenging, and this study sought to explore how coagulation-related biomarkers could help.
- A study involving 214 patients with unprovoked VTE measured several biomarkers at diagnosis, finding that sP-selectin levels were significantly higher in patients with occult cancer.
- Combining high levels of sP-selectin and D-dimer can potentially identify occult cancer with up to 91% specificity, indicating these biomarkers may be useful in clinical settings, although more research is needed.
Article Synopsis
- Most clinical labs use nephelometry or turbidimetry to measure alpha-1 antitrypsin (AAT) levels because these methods are automated and precise, relying on light scattering.
- Nephelometry assesses light scattering by directly measuring the intensity of light that passes through a sample, while turbidimetry measures the reduction in light intensity due to scattering by particles.
- The effectiveness of both methods can be influenced by factors like sample concentration and the size of the particles being measured, with specific protocols and clinical applications discussed for diagnosing AAT deficiency.
Background: Chronic obstructive pulmonary disease (COPD) is a condition resulting from a persistent inflammatory state in the airways even after smoking cessation. Intriguingly, the reasons behind this persistence of the inflammatory influx without smoking exposure have not been fully unraveled. We aimed to explore the hypothesis that systemic inflammation in COPD patients influences lung cell inflammatory response.
View Article and Find Full Text PDFOver recent decades, a number of studies have revealed the possible role of different types of diets, as well as the nutritional elements they are made up of, in the pathogenesis of chronic obstructive pulmonary disease (COPD). To date, dietary factors have been identified to play a role in the prevention of COPD, with evidence from antioxidant nutrients, vitamins, and fiber intake. Additionally, certain dietary patterns such as the Mediterranean diet, together with other Western diets, provide evidence of the influence on COPD development, promoting lung health through nutritional approaches, and giving us an opportunity for intervention.
View Article and Find Full Text PDFBackground: We examined the degree of postprandial triglyceride (TG) response over the day, representing a highly dynamic state, with continuous metabolic adaptations, among normal-weight, overweight and obese patients, according to their metabolically healthy or abnormal status.
Materials And Methods: A total of 1002 patients from the CORDIOPREV clinical trial (NCT00924937) were submitted to an oral fat load test meal with 0·7 g fat/kg body weight (12% saturated fatty acids (SFA), 10% polyunsaturated fatty acids (PUFA), 43% monounsaturated fatty acids (MUFA), 10% protein and 25% carbohydrates). Serial blood test analysing lipid fractions and inflammation markers (high-sensitivity C-reactive protein (hs-CRP)) were drawn at 0, 1, 2, 3 and 4 h during postprandial state.
Objective: To evaluate the impact of oxidative stress and cellular adhesion molecules on ischemic reactive hyperemia (IRH) in patients with OSA.
Materials And Methods: Consecutive patients treated at a sleep laboratory and whose polysomnography showed an apnea hypopnea index (AHI) ≥5 were included in the study. Patients with acute illness receiving vasoactive medications were excluded.