The effects of gluten-free diet versus hypocaloric diet among patients with fibromyalgia experiencing gluten sensitivity symptoms: protocol for a pilot, open-label, randomized clinical trial.

Background: Fibromyalgia is a chronic musculoskeletal pain syndrome characterized by a broad spectrum of manifestations. Patients with fibromyalgia frequently suffer from manifestations similar to those experienced by patients with gluten-related disorders raising the possibility that some patients with fibromyalgia could suffer from underlying gluten sensitivity.

Objective: This study aims to assess whether avoiding gluten among patients with fibromyalgia and gluten sensitivity is beneficial.

Monotherapy or combination therapy for fibromyalgia treatment?

Fibromyalgia is a chronic pain disease whose clinical symptomatology also includes different symptom domains: fatigue, sleep disturbances, morning stiffness, dyscognition, and psychological distress. These associated symptoms usually vary in frequency and intensity from patient to patient. Because the efficacy of monotherapy is limited, more severely affected patients frequently require drug combinations.

Amisulpride in the treatment of fibromyalgia: an uncontrolled study.

Some antipsychotics, including amisulpride, have shown to be effective in the treatment of various painful conditions, lessening pain as well as symptoms of anxiety and/or depression. In this open-label, 12-week study, we explored the efficacy and tolerability of amisulpride in patients with fibromyalgia. We recruited 40 patients, 1 male and 39 females, aged 46.